Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Newly Discovered CD8-fit Cells Could Revolutionize Cancer Treatment

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

30 May 2024

Inverse relationship found between anti-inflammatory macrophages and NK cells/T cells in lung cancer

Single-cell ribonucleic acid sequencing (scRNAseq) and spatial transcriptomics to study cellular organization and interactions within the tumor microenvironment.

30 May 2024

Unmasking XPD’s Mechanism in DNA Damage Detection and Repair

The way the protein XPD recognizes severe DNA damage and regulates its repair was uncovered by researchers at the University of Würzburg, under the direction of Caroline Kisker and Claudia Höbartner.

29 May 2024

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel.

29 May 2024

Novel Protein 'Cloaking' Technique for Enhanced Therapeutic Applications

Cornell University scientists have designed a way to "cloak" proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

29 May 2024

Unlocking the Power of Circadian Rhythms for Enhancing Cancer Immunotherapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

29 May 2024

Cryo-EM Reveals Structural Insights Into ADAM17/iRhom2 Complex

Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease.

24 May 2024

Researchers Develop Strategy to Replace Diseased Blood System Affected by Leukemia

Researchers have developed an approach to "deleting" a blood system affected by leukemia while simultaneously building up a new, healthy system with donor blood stem cells.

24 May 2024

New Chemical Modification Enhances Antisense Oligonucleotide Targeting in CNS Diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

23 May 2024

Exploring Cell-in-Cell Events Across the Tree of Life

In a new review paper, Carlo Maley and Arizona State University colleagues describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another.

22 May 2024

How Immune Cells Decode Cancer's Turbocharged State

When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies.

22 May 2024

The Influence of Inherited Genes on Melanoma Risk

Most people associate skin cancer warnings with sunburn and tanning beds. “Cancer genes” or inherited risks are associated with diseases such as breast and colon cancer.

22 May 2024

PhoreMost Introduces GlueSEEKER Platform for Discovery of Molecular Glue Degraders

PhoreMost Ltd., a leading UK biopharmaceutical company unlocking the next generation of drug targets, today announced the introduction of GlueSEEKER™. The new phenotypic screening platform expands the Company’s capabilities in this emerging therapeutic modality to support the systematic discovery and development of novel molecular glue degraders (MGDs) for targeted protein degradation (TPD).

From PhoreMost 22 May 2024

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Whether loading vincristine sulfate into mesenchymal stem cell-derived exosomes could improve the targeted delivery of the drug specifically to cancer stem cells.

21 May 2024

Study Identifies Ruminococcus gnavus as Key Microbial Partner in Cancer Immunotherapy

Roughly one in five cancer patients benefits from immunotherapy – a treatment that harnesses the immune system to fight cancer.

20 May 2024

Unveiling the Anti-Inflammatory and Anti-Obesity Potential of Menthol-Derived Esters

Obesity and inflammatory diseases are increasing in prevalence and contribute to the growing burden of lifestyle disorders such as diabetes and hypertension. There is a lack of naturally derived alternatives to tackle these issues

20 May 2024

Study Reveals How tRNA Modification Influences Malaria Drug Resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites’ ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

20 May 2024

Discovery of New Cancer Cell Death Pathway Involving Schlafen11 Gene

Chemotherapy kills cancer cells. But the way these cells die appears to be different than previously understood.

17 May 2024

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

16 May 2024

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes.

16 May 2024

Cancer News and Research

Newly Discovered CD8-fit Cells Could Revolutionize Cancer Treatment

Inverse relationship found between anti-inflammatory macrophages and NK cells/T cells in lung cancer

Unmasking XPD’s Mechanism in DNA Damage Detection and Repair

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

Novel Protein 'Cloaking' Technique for Enhanced Therapeutic Applications

Unlocking the Power of Circadian Rhythms for Enhancing Cancer Immunotherapy

Cryo-EM Reveals Structural Insights Into ADAM17/iRhom2 Complex

Researchers Develop Strategy to Replace Diseased Blood System Affected by Leukemia

New Chemical Modification Enhances Antisense Oligonucleotide Targeting in CNS Diseases

Exploring Cell-in-Cell Events Across the Tree of Life

How Immune Cells Decode Cancer's Turbocharged State

The Influence of Inherited Genes on Melanoma Risk

PhoreMost Introduces GlueSEEKER Platform for Discovery of Molecular Glue Degraders

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Study Identifies Ruminococcus gnavus as Key Microbial Partner in Cancer Immunotherapy

Unveiling the Anti-Inflammatory and Anti-Obesity Potential of Menthol-Derived Esters

Study Reveals How tRNA Modification Influences Malaria Drug Resistance

Discovery of New Cancer Cell Death Pathway Involving Schlafen11 Gene

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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