Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Exploring cell and gene based therapies for Parkinson’s disease

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

24 Sep 2021

Researchers identify host entry factor for Rift Valley fever virus

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle. These mosquito-borne outbreaks lead to infection in people working with dead or dying animals, sometimes causing hundreds of human cases and dozens of deaths.

24 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Researchers show how 'bad mucin' contributes to worsening pulmonary conditions

Mucus is an essential protective layer of gel-like liquid composed largely of proteins called mucins throughout our airways.

23 Sep 2021

Study explores the benefits of the MIND diet for older adults

Scientists identified that older adults could take advantage of a specific diet named the MIND diet even when the protein deposits are developed.

23 Sep 2021

Novel process enables 3D imaging of human organs with micrometer resolution

Scientists recently demonstrated a process by which specific cell types in human organs can be investigated with micrometer precision.

15 Sep 2021

Newly identified antibacterial mechanism could inspire novel strategies to combat bacterial pathogens

Similar to how a spider traps its prey, the cells of the human immune system cooperate to trap and “eat” bacteria.

14 Sep 2021

Pairing microscopy with AI to develop a rapid, accurate COVID-19 test

Beckman researchers paired microscopy with artificial intelligence to develop a COVID-19 test that's fast, accurate, and cost-effective. All we need to do is say "ahh."

13 Sep 2021

Researchers engineer CAR T cells to enhance their function

Chimeric antigen receptor (CAR) T cell therapy employs engineered T cells to treat certain kinds of cancers.

7 Sep 2021

Drug-resistant Salmonella serovar Enteritidis genome sequenced by experts

Scientists sequenced the genome of a virulent Salmonella Enteritidis strain and discovered that it was both antibiotic-resistant and could affect people.

7 Sep 2021

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

The emergence of the COVID-19 pandemic in the United States in early 2020 left researchers struggling to identify lab models of SARS-CoV-2 infection.

From UC San Diego 2 Sep 2021

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.

25 Aug 2021

Scientists isolate monoclonal antibodies against alphaviruses

A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.

From Vanderbilt University 24 Aug 2021

Researchers identify potent antibody that protects against a wide range of viral variants

The virus that causes COVID-19 today is not the same as the one that first sickened people way back in December 2019.

23 Aug 2021

Novel genome-editing technology to mitigate Alzheimer’s disease

Around 500,000 patients in China alone are considered to be living with a hereditary form of Alzheimer’s disease (AD).

19 Aug 2021

COVID-19 vaccine-induced antibody protects against delta variant

Despite causing a surge in infections this summer that has resulted in thousands of hospitalizations and deaths, the delta variant of the virus that causes COVID-19 is not particularly good at evading the antibodies generated by vaccination, according to a study by researchers at Washington University School of Medicine in St. Louis.

18 Aug 2021