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Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Discovering Novel Senolytic Compounds with the Power of Artificial Intelligence

A new publication in the May issue of Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, demonstrates the power of artificial intelligence (AI) to discover novel senolytic compounds, a class of small molecules under intense study for their ability to suppress age-related processes such as fibrosis, inflammation and cancer.

8 May 2023

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.

3 May 2023

Genes Responsible for Aging Identified in Nematodes

The USask research team uncovered a pair of genes involved in removing cells of toxins that build in the body and cause aging while working with small nematode worms called C. elegans. The researchers discovered that inactivating genes named CCF-1 and PAL-1 caused nematodes to die 50% faster than usual.

3 May 2023

First Chronic Wound Murine Model to Profile the Effects of Cellular Senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

Previously Unknown Regulatory Mechanism for Circadian and Temperature Signaling Pathways Revealed

Ever wondered why people become tired when the sun goes down? What causes some flower petals to open during the day and close at night? Or how monarch butterflies ascertain when to migrate south?

2 May 2023

Markers Indicating Early Signs of Schizophrenia Identified

For the first time, a global study group headed by investigators at Virginia Commonwealth University has found markers that might point out early if a person is susceptible to schizophrenia in the early stage itself.

28 Apr 2023

Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

Recent research published in the journal eLife proposes a theory for how cancer cells might actively adapt to the immune system to become resistant to immunotherapy.

27 Apr 2023

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks.

26 Apr 2023

Green Algae in Swedish Lakes Offer New Clues to the Amazing Paths of Evolution

By studying green algae in Swedish lakes, a research team, led by Lund University in Sweden, has succeeded in identifying which environmental conditions promote multicellularity.

26 Apr 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

The mathematical and biological mechanisms underlying the rugged structures at cell boundaries present in tissues like the kidneys and nasal glands have been discovered.

26 Apr 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

Changes in Gut Microbiomes of Astronauts May be Linked to Bone Loss

In space, the bone density of both the human astronauts and rodent variety decreases. Scientists published this study on April 19th, 2023, in the journal Cell Reports. It says that alterations to the gut microbiomes of space travelers may be linked to this bone loss.

21 Apr 2023