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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Silencing a key protein to “domesticate” COVID-19 virus

When cells in the human body are invaded by a virus, they send a signal to adjacent cells to boost their antiviral defenses to stop the spread of infection.

25 Mar 2021

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Using electron cryo-tomography, researchers have created the first high-resolution 3D image of the sarcomere.

25 Mar 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

Specific enzyme can delay the growth and spread of neck and head carcinomas

Scientists were able to considerably delay the growth and proliferation of tumors in mice and improve the effectiveness of immunotherapy.

24 Mar 2021

Stem cell therapy could help restore debilitating muscle loss that happens with age

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

24 Mar 2021

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

24 Mar 2021

Study into cellular filopodia could optimize cancer therapy and wound closure

Imagine using only a finger to heal a wound! It seems like science fiction, reminding one of the 1982 movie E.T.

23 Mar 2021

Bacteria residing within tumor cells may boost cancer immunotherapy

Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. In a new study published in Nature, researchers at the Weizmann Institute of Science and their collaborators have discovered that the immune system "sees" these bacteria and shown they can be harnessed to provoke an immune reaction against the tumor.

23 Mar 2021

Processed meat consumption associated with increased risk of dementia

Scientists from the University of Leeds's Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent to one rasher of bacon, is associated with a 44% increased risk of developing the disease.

23 Mar 2021

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

23 Mar 2021

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Oncotarget published "Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells" which reported that although the molecular mechanism behind the antitumor properties of NSAIDs has been largely attributed to inhibition of cyclooxygenases , several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.

23 Mar 2021

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

A genetic engineering approach has helped scientists to drastically decrease the levels of tau protein.

22 Mar 2021

Study advances CAR T cell therapy targeted at cancer

Cancer immunotherapy involves the activation of cells in the patient’s own immune system to fight tumor cells.

19 Mar 2021

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

A study headed by UCM reports that polymorphisms in gene TGFB1 and low plasma levels of protein TGFB1 serve as biomarkers for the gastric adenocarcinoma prognosis.

19 Mar 2021

Immune receptor proteins can help treat autoimmune diseases

TARM1 is a receptor protein, whose function in the working of the immune system is not known yet. Now, in a new research work, Japanese researchers have analyzed mouse models to investigate the promising role of TARM1 protein in the pathogenesis of rheumatoid arthritis.

From Tokyo University of Science 18 Mar 2021

New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Researchers identify address codes in odorant receptor proteins for the first time

A team of scientists led by Dietmar Krautwurst from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now identified address codes in odorant receptor proteins for the first time.

18 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

Study identifies novel mechanism by which hair follicles lose regenerative capabilities

Hair grows from stem cells residing in hair follicles. During aging, the capability of hair follicles to grow hair is successively lost, leading to hair thinning and ultimately hair loss.

17 Mar 2021

Protein News and Research

Further Reading

Silencing a key protein to “domesticate” COVID-19 virus

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Gender difference accounts for major psychiatric disorders

Specific enzyme can delay the growth and spread of neck and head carcinomas

Stem cell therapy could help restore debilitating muscle loss that happens with age

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Study into cellular filopodia could optimize cancer therapy and wound closure

Bacteria residing within tumor cells may boost cancer immunotherapy

Processed meat consumption associated with increased risk of dementia

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

Study advances CAR T cell therapy targeted at cancer

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

Immune receptor proteins can help treat autoimmune diseases

New highly sensitive RNA detection method advances in situ transcriptomics

Researchers identify address codes in odorant receptor proteins for the first time

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Study shows how human viruses are better adapted to infect certain tissues

Study identifies novel mechanism by which hair follicles lose regenerative capabilities

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