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New findings help to better understand the genetics of neuropsychiatric disorders

A new study led by NorthShore University HealthSystem (NorthShore) and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

5 Aug 2020

Newly discovered 'mutation fog' linked to normal DNA repair process

Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer.

5 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Identifying a new genetic cause of inherited neuropathy

Inherited mutations in a gene that keeps nerve cells intact were shown, for the first time, to be a driver of neuropathy known as Charcot-Marie-Tooth disease.

4 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

New study can help develop longevity-promoting drugs

Scientists have successfully dialed up and down the lifespan of creatures by changing the activity of proteins present in roundworm cells.

4 Aug 2020

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

3 Aug 2020

Ecological stress within freshwater species can be detected with DNA metabarcoding

DNA or eDNA, for example, river water or, as in the case of the study by the team from the University of Duisburg-Essen (Essen, Germany) within the German Barcode of Life project (GBOL II): Vera Zizka, Dr Martina Weiss and Prof Florian Leese, from individuals in bulk samples.

3 Aug 2020

Detailed 3D structure provides a roadmap for tweaking CRISPR-Cas9–guided base editors

Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy.

31 Jul 2020

Novel therapeutics targeting primary cilia may reverse neurodevelopmental disorders

Primary cilia are structures that act like antennas for cells to identify signals and occur less in mice affected by Fragile X syndrome since birth.

31 Jul 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020

Understanding the structure of SARS-CoV-2 proteins may lead to novel drugs

COVID-19 is a disease caused by an RNA virus called SARS coronavirus 2 (SARS-CoV-2), that is, a virus that employs RNA to preserve its genetic data.

31 Jul 2020

Researchers create a new mouse model for studying glioblastoma

More than 200 genes with novel and known roles in glioblastoma - the most aggressive type of brain cancer - offer promising new drug targets.

30 Jul 2020

Researchers map DNA methylation changes to study developmental disorders

Researchers performed a study in which they created a total of 168 new maps of chemical marks on DNA strands, known as methylation, in developing mice.

30 Jul 2020

Researchers show how gut microbiomes change the nature of cancer mutations

It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to "attract" cancer?

30 Jul 2020

Scientists use computational biology to identify functional elements in the human genome

UMass Medical School researchers Zhiping Weng, PhD, and Jill Moore, PhD, and MD/PhD students Michael Purcaro and Henry Pratt are lead authors on the latest publication of data from the ambitious ENCODE project.

30 Jul 2020

A new cell-based gene therapy approach to correct hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

29 Jul 2020

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

29 Jul 2020

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Olympus, a leading manufacturer of high-end research microscopes, and Cytosurge, a precision manufacturer of cell manipulation technologies, have entered a co-marketing agreement to become a complete system provider to the scientific community’s growing need for next-generation single-cell and CRISPR genetic manipulation solutions.

From Cytosurge AG 29 Jul 2020

Genetic News and Research

New findings help to better understand the genetics of neuropsychiatric disorders

Newly discovered 'mutation fog' linked to normal DNA repair process

New study may offer a novel, potential target for treating breast cancer

Identifying a new genetic cause of inherited neuropathy

Old part of immune system may influence severity of COVID-19

Researchers develop CAR-T cell therapy based on TCR signal transduction

New study can help develop longevity-promoting drugs

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Ecological stress within freshwater species can be detected with DNA metabarcoding

Detailed 3D structure provides a roadmap for tweaking CRISPR-Cas9–guided base editors

Novel therapeutics targeting primary cilia may reverse neurodevelopmental disorders

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Understanding the structure of SARS-CoV-2 proteins may lead to novel drugs

Researchers create a new mouse model for studying glioblastoma

Researchers map DNA methylation changes to study developmental disorders

Researchers show how gut microbiomes change the nature of cancer mutations

Scientists use computational biology to identify functional elements in the human genome

A new cell-based gene therapy approach to correct hemophilia A

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

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