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Gene variations that regulate dopamine levels may influence the mobility of elders

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

13 Oct 2020

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Every eukaryotic organism contains the so-called transposons, which are abundant DNA-elements.

13 Oct 2020

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Scientists from the UK's foremost agricultural research institutes have teamed up to create a new UK Crop Microbiome Cyrobank (UK-CMCB) to safeguard future research and facilitate the sustainable yield improvement of the UK's six major food crops including barley, oats, oil seed rape, potato, sugar beet and wheat.

12 Oct 2020

Researchers examine cooperative tumorigenic effects of targeted deletions of tumor suppressors

Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.

12 Oct 2020

Genomes provide insights into fig-wasp coevolution

Banyan trees are fig trees that begin their life as an epiphyte. The most noticeable feature of banyan Ficus species is their extraordinary aerial roots, which enable them to live as hemi-epiphytes, as do the strangler figs often seen in tropical forests.

12 Oct 2020

Scientists shed light on immune evasion strategy used by malaria-causing parasite

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi.

12 Oct 2020

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

12 Oct 2020

Too many genetic exchanges impede chromosome segregation into eggs

The exchange of DNA between chromosomes during the early formation of sperm and egg cells normally is limited to assure fertility.

9 Oct 2020

Study shows thymoquinone compound selectively kills prostate cancer cells

According to a new study reported in the Oncogene journal, the thymoquinone (TQ) compound selectively destroys prostate cancer cells at advanced phases.

9 Oct 2020

Newly developed biodegradable microneedles deliver genes into the skin

Gene therapy offers an excellent potential for treating specific types of genetic defects and cancer, immunological diseases, infections, and wounds.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

New algorithm sharpens focus of world's most powerful microscopes

We have all seen in a TV show where a detective is reviewing grainy security footage, spots a person of interest, and asks a technician to "enhance that."

8 Oct 2020

Study confirms genetic link in cerebral palsy

A research team has found further evidence that rare gene mutations can cause cerebral palsy, findings which could lead to earlier diagnosis.

8 Oct 2020

Microneedles For Therapeutic Gene Delivery

There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections.

7 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Scientists fine-tune plasma treatment to optimize plant growth and yield

Ever since scientists discovered that plasma treatment leads to faster growth and higher yields of some agricultural crops, physicists, chemists, and biologists have been working together to tease out the mechanisms driving this phenomenon.

7 Oct 2020

Using CRISPR/Cas9 technology in trees for a bio-based economy

Researchers led by prof. Wout Boerjan (VIB-UGent Center for Plant Systems Biology) have discovered a way to stably finetune the amount of lignin in poplar by applying CRISPR/Cas9 technology.

7 Oct 2020

Researchers demonstrate new method to increase catalytic activity of cyanobacteria

Although cyanobacteria are known to stain water green through their unique pigments, they are colloquially referred to as “blue-green algae.”

6 Oct 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

MIT engineers develop a method to turn off specific genes in bone marrow cells

Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells.

From Massachusetts Institute of Technology (MIT) 6 Oct 2020

Genetic News and Research

Gene variations that regulate dopamine levels may influence the mobility of elders

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Researchers examine cooperative tumorigenic effects of targeted deletions of tumor suppressors

Genomes provide insights into fig-wasp coevolution

Scientists shed light on immune evasion strategy used by malaria-causing parasite

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Too many genetic exchanges impede chromosome segregation into eggs

Study shows thymoquinone compound selectively kills prostate cancer cells

Newly developed biodegradable microneedles deliver genes into the skin

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

New algorithm sharpens focus of world's most powerful microscopes

Study confirms genetic link in cerebral palsy

Microneedles For Therapeutic Gene Delivery

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

Scientists fine-tune plasma treatment to optimize plant growth and yield

Using CRISPR/Cas9 technology in trees for a bio-based economy

Researchers demonstrate new method to increase catalytic activity of cyanobacteria

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

MIT engineers develop a method to turn off specific genes in bone marrow cells

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