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Scientists develop novel microcarrier for large-scale cell production

Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a novel microcarrier for large-scale cell production and expansion that offers higher yield and cost-effectiveness compared to traditional methods, and reduces steps required in the cell retrieval process.

30 Oct 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Research projects receive BTCA awards to develop new drugs

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

From Harvard Medical School 30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

New research shows ultrasound treatment can destroy cancer cells without surgery

Focusing ultrasound energy on a target site in the body to generate heat can burn and destroy the tissue in the site without a surgical procedure.

27 Oct 2020

New method for producing FTVI enzyme could enhance therapeutic potential of cord blood transplants

A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.

23 Oct 2020

Rutgers researchers discover gene markers linked to metastatic prostate cancer

Rutgers researchers have discovered human gene markers that work together to cause metastatic prostate cancer - cancer that spreads beyond the prostate.

From Rutgers University 20 Oct 2020

Researchers demonstrate the impact of epithelial cells, mammary microenvironment on breast cancer cells

The cover for issue 30 of Oncotarget features Figure 4, "RNAseq results demonstrating differences between normal, cancer, and redirected cells," by Frank-Kamenetskii, et al. which reported that the influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on breast cancer cells has not.

19 Oct 2020

New mechanism of metastatic cancer cells discovered in substrates of different stiffness

During metastasis, cancer cells actively interact with microenvironments of new tissues. How metastatic cancer cells respond to new environments in the secondary tissues is a crucial question in cancer research but still remains elusive.

19 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Stem cells that promote bone repair can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

13 Oct 2020

Bone destruction caused by too little sugar

Bone marrow cancer is currently an incurable disease that affects about 400 people in Norway every year. Professor Therese Standal at NTNU has now found an important reason for bone destruction in people with this disease.

12 Oct 2020

Reducing the harvest period of stem cell sheets to two days

Stem cells are cell factories that constantly divide themselves to create new cells. Implanting stem cells in damaged organs can regenerate new tissues.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Bone News and Research

Scientists develop novel microcarrier for large-scale cell production

'Training’ the innate immunity may improve the success of immunotherapy

Research projects receive BTCA awards to develop new drugs

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

New research shows ultrasound treatment can destroy cancer cells without surgery

New method for producing FTVI enzyme could enhance therapeutic potential of cord blood transplants

Rutgers researchers discover gene markers linked to metastatic prostate cancer

Researchers demonstrate the impact of epithelial cells, mammary microenvironment on breast cancer cells

New mechanism of metastatic cancer cells discovered in substrates of different stiffness

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Stem cells that promote bone repair can also generate arthritic bone spurs

Bone destruction caused by too little sugar

Reducing the harvest period of stem cell sheets to two days

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

Dried plum diet prevents bone loss associated with spinal cord injury

New drug shows promise in the treatment of neuroblastoma

MIT engineers develop a method to turn off specific genes in bone marrow cells

"Stretching Rack" For Cells

Researchers identify new way to treat chronic myelogenous leukemia

Combining stem cell therapy with educational intervention can help children with autism

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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