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Scientists analyze the molecular machinery of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Circulating tumor cells found to form clusters that cause breast cancer metastases

A new study reports that circulating tumor cells that exhibit the features of stem cells employ ICAM1 to enable the formation of CTC clusters.

24 Sep 2021

Discovery may offer a promising new path for the study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Microglial cells join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

Llamas' nanobodies could provide a new frontline treatment against Covid-19

A unique type of tiny antibody produced by llamas could provide a new frontline treatment against Covid-19 that can be taken by patients as a simple nasal spray.

23 Sep 2021

Prions may help yeast cope with rapidly changing environmental conditions

Prions are proteins found in the brain and familiar for their role in causing disease.

23 Sep 2021

Potential biomarkers help diagnose progressive stages of liver disease

Results of national research pinpointed potential biomarkers that could ultimately be employed for the diagnosis of progressive stages of liver disease.

23 Sep 2021

Researchers provide novel treatment target for common skin condition

Recent research indicates that a familiar inflammatory skin condition might arise due to inadequately regulated sex hormones.

23 Sep 2021

Experts explore the organization of cancer cells and the influence of drug treatment

The changes that occur in individual cancer cells in due course detail the varied development of brain tumors.

23 Sep 2021

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

22 Sep 2021

Premature aging of the tracheobronchial stem cells could contribute to chronic lung disease

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

CSHLP releases new book on the arsenal of memory T-cells

Cold Spring Harbor Laboratory Press (CSHLP) announced the release of T-Cell Memory, available on its website in hardcover and eBook formats.

21 Sep 2021

Scientists find two proteins that pair up to build lifelines to cancer cells

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

21 Sep 2021

Researchers find a new way to counter immunosuppressive effect in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

21 Sep 2021