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Researchers identify new set of protein biomarkers for cancer using breast milk

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

5 Apr 2022

Older rats more vulnerable to caffeine-induced ventricular tachyarrhythmia than younger ones

The Food and Drug Administration recommends healthy adults not exceed 400 milligrams (mg) of caffeine-; approximately four cups of brewed coffee-; a day.

4 Apr 2022

Plant compound may be a good therapeutic candidate for treating food allergies

Researchers combined advanced computational methods with experimental studies to gain new insight, at the cell level, into how the plant compound formononetin might be used to treat food allergies.

4 Apr 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

Researchers show how proteins form DNA-repair mechanism in living bacteria

Two recent research have shown a completely new perspective of how bacterial cells repair broken parts of their DNA (lesions).

From New York University (NYU) 1 Apr 2022

Study highlights the importance of membrane composition of targeted cells

Bacteria, fungi, and yeast are very good at excreting useful substances such as weak acids. One way in which they do this is through passive diffusion of molecules across the cell membrane. At the same time, cells need to prevent leakage of numerous small molecules.

29 Mar 2022

Scientists create powerful new method for generating protein drugs

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

28 Mar 2022

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

For decades, scientists have been trying to unravel an enduring mystery of structural biology: Why do two otherwise identical protein forms found in everything from plants, amphibians and human beings hang onto a slight variation across the mighty span of evolution?

21 Mar 2022

Researchers demonstrate how sperms defend their membranes from oxidation

A team of researchers compared lipid profiles of sperm to learn more about their vulnerability to harmful oxidation and antioxidant capacity in different species’ semen.

21 Mar 2022

New database provides extensive information on kinase-associated neural protein phosphorylation

Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.

17 Mar 2022

Macrophages show altered inflammatory, metabolic expression months after mild COVID-19

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

15 Mar 2022

Researchers uncover the genetic variant link to fatal esophageal disease in dogs

Researchers from Clemson University have found a genetic variation linked to a potentially fatal esophageal disease common in German shepherd dogs.

14 Mar 2022

New tools for measuring the biological ages of various organ systems

It's common to say that someone looks either younger or older than their chronological age, but aging is more than skin deep.

9 Mar 2022

Research points to a common thread linking diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

7 Mar 2022

New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Researchers identify universal patterns in the chemistry of life

The only references we have for "life" are the forms we know on Earth. Astrobiologists suspect that the search for alien life, and even for the origins of life on Earth, may require a broader scope.

1 Mar 2022

Study reveals the power of ketone bodies

The immune system has its cells all around the body, and they are constantly doing their work even if the body is in great shape.

22 Feb 2022

Researchers engineer strains of nitrogen-fixing soil bacterium to produce ammonia

Researchers from Washington State University have engineered strains of the ubiquitous, nitrogen-fixing soil bacterium Azotobacter vinelandii to produce ammonia and excrete it at high concentrations, transferring it into crop plants in lieu of conventional chemical fertilizers.

18 Feb 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022