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Human Antibodies Offer Hope for Improved Black Widow Antivenom

Sera produced from horses can be used to treat serious illnesses caused by black widow bites. But this approach is not totally secure. To address this, scientists have produced entirely human antibodies that are capable of neutralizing the European black widow's alpha-latrotoxin.

13 Jun 2024

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Whether forcing adult cardiomyocytes to reverse from the oxidative phosphorylation phenotype to the glycolysis phenotype would also restore their mitotic ability.

13 Jun 2024

Exploring the Use of Weakened Viruses for Cancer Treatment

Scientists at Northwestern Medicine have found that an attenuated virus can aid in the elimination of cancer in mice. Furthermore, mice given this virus treatment had a higher lifetime tumor-prevention rate.

12 Jun 2024

AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

Explore the groundbreaking work of Mark Bear, a leading figure in neuroscience, as he shares insights on synaptic plasticity, learning, and the future of neurological research.

12 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

Researchers at the Broad Institute of MIT and Harvard have enhanced a gene-editing technology, enabling it to efficiently insert or substitute entire genes in the genome of human cells.

11 Jun 2024

CARA Benchmark Set to Revolutionize Data-Driven Drug Discovery Methods

A compound activity prediction benchmark they curated for real-world, practical applications called Compound Activity benchmark for Real-world Applications (CARA).

11 Jun 2024

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson's disease.

10 Jun 2024

Study Reveals Diversity of DNA Transposons and Expands Genome Engineering Toolbox

In a study published in Cell, a research team led by Zhang Yong'e and WANG Haoyi from the Institute of Zoology of the Chinese Academy of Sciences has characterized the diversity of DNA transposons and expanded the genome engineering toolbox.

7 Jun 2024

Cellular Architecture Dictates T Cell Fate in Immune Response

From the outside, most T cells look the same: small and spherical. Now, a team of researchers led by Berend Snijder from the Institute of Molecular Systems Biology at ETH Zurich has taken a closer look inside these cells using advanced techniques.

7 Jun 2024

Breakthrough Study Identifies Critical Protein for Blood Stem Cell Self-Renewal

UCLA scientists have identified a protein that plays a critical role in regulating human blood stem cell self-renewal by helping them sense and interpret signals from their environment.

6 Jun 2024

Coordinated Proteins Aid the Immune System in Detecting and Destroying Threats

Bacteria, parasites, and viruses—the immune system tackles them all. Cells known as macrophages are at the forefront of the human immune response, recognizing intruders and controlling how the entire immune system responds.

6 Jun 2024

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

A team of researchers from Case Western Reserve University School of Medicine has created a novel method for target DNA sequence amplification, testing, and analysis.

6 Jun 2024

New Computational Method STew Bridges Gap Between Gene Expression and Spatial Biology

In disease research, it's important to know gene expression and where in a tissue the expression is happening, but marrying the two sets of information can be challenging.

5 Jun 2024

Researchers Advance Single-Molecule DNA Sequencing Techniques

In recent years, technologies that allow scientists to investigate a person's DNA at single-molecule resolution have greatly increased the knowledge of the human genome, microbiome, and the genetic basis of disease.

5 Jun 2024

Brain Organoids Emerge as Powerful Tool for Drug Discovery in Mitochondrial Disease

The use of brain organoids in screening for drugs against mitochondrial diseases, which have hitherto presented challenges in treatment.

4 Jun 2024

Stem Cell Factor Levels Show Promise in Predicting Successful IVF for Endometriosis

The ability of serum levels of stem cell factor to indicate the quality of oocyte and blastocyst development.

4 Jun 2024

"Cervix-on-a-Chip" Offers Promise for New Bacterial Vaginosis Treatments

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

3 Jun 2024

Arrowhead's Plozasiran Reduces Triglyceride Rich Lipoproteins in Patients with Mixed Hyperlipidemia

Arrowhead Pharmaceuticals, Inc. today announced results from the Phase 2b double blind, randomized MUIR study of investigational plozasiran (formerly ARO-APOC3) in patients with mixed hyperlipidemia.

3 Jun 2024

Clinical News and Research

Human Antibodies Offer Hope for Improved Black Widow Antivenom

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Exploring the Use of Weakened Viruses for Cancer Treatment

AI Uncovers Rare Mutations with Major Impact on Heart Health

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

CARA Benchmark Set to Revolutionize Data-Driven Drug Discovery Methods

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Study Reveals Diversity of DNA Transposons and Expands Genome Engineering Toolbox

Cellular Architecture Dictates T Cell Fate in Immune Response

Breakthrough Study Identifies Critical Protein for Blood Stem Cell Self-Renewal

Coordinated Proteins Aid the Immune System in Detecting and Destroying Threats

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

New Computational Method STew Bridges Gap Between Gene Expression and Spatial Biology

Researchers Advance Single-Molecule DNA Sequencing Techniques

Brain Organoids Emerge as Powerful Tool for Drug Discovery in Mitochondrial Disease

Stem Cell Factor Levels Show Promise in Predicting Successful IVF for Endometriosis

"Cervix-on-a-Chip" Offers Promise for New Bacterial Vaginosis Treatments

Arrowhead's Plozasiran Reduces Triglyceride Rich Lipoproteins in Patients with Mixed Hyperlipidemia

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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