Efficacy News and Research

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Finding better treatments to eradicate infection caused by H. pylori bacterium

Helicobacter pylori (H. pylori) is one of the most common bacterial infections worldwide, affecting more than 40 % of the population and is one of the causes of digestive symptoms, such as epigastric discomfort, heaviness or bloating of the stomach, or of other more serious diseases, such as the development of gastric and duodenal ulcers, gastric lymphoma or gastric cancer.

30 Nov 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Anti-idiotype antibodies may explain the long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection.

From The University of California, Davis 26 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Study: Forgotten antibiotic led to lower selection of resistant bacteria

A forgotten antibiotic, temocillin, led to lower selection of resistant bacteria than the standard treatment for febrile urinary tract infection, in a study published in The Lancet Infectious Diseases.

29 Oct 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Ghent University’s concentrated on a technique for the safe engineering of therapeutic cells with photothermal nanofibers for the past decade.

26 Oct 2021

Experts develop antibodies that effectively remove senescent cells

The reason why some people age worse than others and develop diseases linked to the aging mechanism is largely unknown.

22 Oct 2021

Identification of genetic variant provides a big step for precision medicine in dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

High tumor-infiltrating lymphocytes could indicate a better chance of survival in esophageal cancer

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment.

From Osaka University 19 Oct 2021

Novel computationally modeled proteins help control cellular processes

Doctoral assistant Sailan Shui loves to experiment with proteins, activating and deactivating them similar to turning on and off the light switches.

19 Oct 2021

Researchers develop a novel sensor to detect chemical changes in immune cells

Three chemists from the Indiana University Bloomington developed a novel sensor to identify chemical changes in immune cells at the time of the pathogen breakdown.

13 Oct 2021

New technology efficiently delivers immune checkpoint inhibitors for treating brain tumors

Multi-institutional researchers have succeeded in efficiently delivering an immune checkpoint inhibitor (ICI) into the mouse brain, confirming its high efficacy and specificity in treating orthotopically transplanted mice with glioblastoma (GBM). The research was published in Nature Biomedical Engineering.

12 Oct 2021

Experts create “living medicine” to combat biofilms on medical implants

Scientists have developed the first “living medicine” to treat antibiotic-resistant bacteria thriving on medical implants’ surfaces.

8 Oct 2021

RedShift BioAnalytics Celebrates Opening of StructIR Scientific Services Lab with the Launch of the StructIR Lab Grant Program

RedShift BioAnalytics announced the opening of their scientific services lab, StructIR Lab.

From RedShiftBio 7 Oct 2021

Clinical efficacy of CAR-T cells depends on chemical modifications, says study

One in five cancers affects lymph nodes and blood cells resulting in lymphomas and leukemias, respectively.

7 Oct 2021

High levels of polyunsaturated fatty acids in liver cells linked to hepatitis C virus resistance

Hepatitis C virus thrives in humans for years, damaging the liver by causing chronic inflammation, eventually resulting in cirrhosis and liver cancer.

4 Oct 2021

Researchers identify 14 genes responsible for obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain. The findings pave the way for treatments to combat a health problem that affects more than 40% of American adults.

4 Oct 2021

Novel Assay Platform for 3D Microfluidic Cancer Research

AMSBIO have supplied custom Chimeric antigen receptor (CAR)-T products to the University of Strathclyde (UoS) in Glasgow, UK, and ScreenIn3D Ltd, allowing them to perform novel immune-oncology assays in 3D microfluidic cancer models.

From AMS Biotechnology 1 Oct 2021

Researchers develop novel antibacterial nanomaterial to treat skin infections

Researchers at the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague) and the Technical University of Liberec in collaboration with researchers from the Institute of Microbiology of the CAS, the Department of Burns Medicine of the Third Faculty of Medicine at Charles University (Czech Republic), and P. J. Šafárik University in Košice (Slovakia) have developed a novel antibacterial material combining nonwoven nanotextile and unique compounds with antibacterial properties.

1 Oct 2021