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Discovery of heat-sensing gene could help crops to cope better with climate change

By 2050 global warming could reduce crop yields by one-third. UC Riverside researchers have identified a gene that could put the genie back in the bottle.

7 Apr 2021

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Tumor-inhibiting protein p53 boosts gene expression by bringing together nuclear speckles and DNA

Scientists at the University of Pennsylvania headed a group of researchers to unravel the functions of the so-called “nuclear speckles”.

6 Apr 2021

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

The CRISPR-Chip technology was first introduced in 2019 by Dr. Kiana Aran, an Assistant Professor at Keck Graduate Institute (KGI).

6 Apr 2021

Researchers use single-cell RNA sequencing to study the development of leaves

How do we become a complex, integrated multicellular organism from a single cell? While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

New automated process uses ultrashort peptides to print hydrogel scaffolds

A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.

6 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

A pre-clinical study for melanoma and neuroblastoma shows that a customized tumor cell vaccine technique that targets Myc oncogenes coupled with checkpoint therapy produces an active immune response that bypasses antigen selection and immune privilege.

5 Apr 2021

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

A research team from Italy has discovered a pair of microRNA molecules that assist in maintaining a population of cancerous stem cells that fuel the growth of breast cancers and trigger tumor relapse after treatment.

5 Apr 2021

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

From UC San Diego 5 Apr 2021

Novel device can help treat type I diabetes mellitus

Type I Diabetes Mellitus, also called T1D, is an autoimmune disorder that results in an irreversible loss of insulin-producing beta-cells found in the pancreas.

2 Apr 2021

New mechanism of transcriptional regulators influences tumor development

The Wistar Institute scientists have discovered a novel mechanism of transcriptional regulation of cellular senescence that promotes the release of inflammatory molecules that, in turn, affect tumor growth by changing the surrounding microenvironment.

2 Apr 2021

Cell News and Research

Discovery of heat-sensing gene could help crops to cope better with climate change

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

Microfluidic probe sends free radicals on live cells

Tumor-inhibiting protein p53 boosts gene expression by bringing together nuclear speckles and DNA

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

Researchers use single-cell RNA sequencing to study the development of leaves

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

High expression of cell death genes linked to increased risk of dying early from lung cancer

New automated process uses ultrashort peptides to print hydrogel scaffolds

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

Novel device can help treat type I diabetes mellitus

New mechanism of transcriptional regulators influences tumor development

Discovering a new genetic mutation in Schizophrenia

Study reveals the evolution of the human gut microbiota

Key protein could block the most common cause of food poisoning

Innovative computational model of cells could help better understand neurodevelopmental disorders

Targeting epigenetic mechanisms to advance pharmacological treatments for alcoholism

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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