Cytoplasm News and Research

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Mechanism of Pathogenic Fungus Aspergillus fumigatus Unveiled

An international team of researchers, led by Professor Gustavo Goldman of the University of São Paulo and Maynooth University's Dr Özgür Bayram, has unveiled ground-breaking findings on Aspergillus fumigatus, which can cause deadly disease in humans.

5 Jan 2024

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

Novel Endogenous Acid Sensor and a Calcium Store Found in Plant Guard Cells

When plants are infected by pathogens, suffer from a lack of water or have to react to other external stimuli, the first thing they do is increase the proton and calcium concentration in the affected cells.

18 Dec 2023

Non-Invasive Technology for the High-Throughput Characterization of Cancer Cells

Monitoring cancer cells effectively can help physicians with treatment and management, thus reducing cancer-related mortality.

11 Dec 2023

Unraveling the Molecular Basis of SIDT1 and SIDT2 in C. elegans

New work thoroughly characterizes the structural features of human SIDT1 and SIDT2, revealing their existence as dimers in vitro and their tendency to form dimers or higher-order oligomers in their natural environment.

23 Nov 2023

The Exclusome, A New Mammalian "Container"

We speak to Dr. Ruth Kroschewski about new research that details the existence of an 'exclusome', a cytoplasmic container that appears to explain where extra-chromosomal DNA goes once it is in a cell.

24 Oct 2023

Scientists Develop Novel Glycoengineering Platform to Revolutionize Vaccine and Therapeutic Production

A novel glycoengineering platform, created by the laboratory of Assistant Professor Chris Lok-To Sham from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), is poised to revolutionize future production of vaccines and therapeutics to fight infectious diseases.

17 Oct 2023

MIT Chemists Discover Structure of SARS-CoV-2 Ion Channel in Open State

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

16 Oct 2023

DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

The Pathogenic Mechanism Underpinning MEPAN Syndrome

New research published in Nature Metabolism discovered the pathogenic mechanism driving mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome, a rare pediatric neurodegenerative disease.

1 Sep 2023

Changes in RNA Induced by Different Chemical Modifications

RNA is essential for protein synthesis in the cell. According to a new study, RNA can be modified by numerous chemical modifications, the purpose of which is unknown to most people.

28 Aug 2023

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

23 Aug 2023

Potential Strategies for Slowing Cognitive Deterioration in Age-Associated Neurodegenerative Conditions

As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases.

3 Aug 2023

Cornell Researchers Develop a Multimodal Platform to Image Biohybrids

When considering ways to sustainably generate environmentally friendly products, bacteria might not immediately spring to mind.

31 Jul 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Salmonella Employs Unique Tactics to Escape Cellular Defense

Salmonella enterica, a disease-causing bacterium, employs a variety of strategies to evade the human body’s defense mechanisms, much like thieves.

29 May 2023

Investigators Characterize and Name the Protein Domain that Governs Collagen Transport

Discovery of the MOTH domain offers insights into evolution. This is because both insects and vertebrates need collagen in their connective tissue.

23 May 2023

New Insights Into How Diverse Chromosomal Alterations Form and Drive Cancer Development

The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells.

12 May 2023

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

5 May 2023

Study Reveals That Transcriptional Buffering Occurs in Rett Syndrome Nerve Cells

Every cell in our body is able to turn genes (DNA) on or off, producing RNA, but when genes are 'turned on' to the wrong level it can result in a variety of health conditions.

3 May 2023