Disease Modeling News and Research

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New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

12 Jan 2022

Research highlights opportunities to expand the manufacture of stem cells in space

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

3 Jan 2022

Researchers employ hepatic organoids for disease modeling

Associate Professor Tamer Önder created and analyzed the hepatic organoid culture system utilizing human induced pluripotent stem cell as an intermediate.

8 Nov 2021

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

The emergence of the COVID-19 pandemic in the United States in early 2020 left researchers struggling to identify lab models of SARS-CoV-2 infection.

From UC San Diego 2 Sep 2021

Researchers create non-invasive imaging technology to predict stem cell differentiation

Stem cell research exhibits significant potential for regenerative therapies and treatments to fight against cardiovascular disease.

29 Jul 2021

Researchers explore new ways to culture living heart cells for microgravity research

As part of preparing for an experiment aboard the International Space Station, researchers explored new ways to culture living heart cells for microgravity research. They found that cryopreservation, a process of storing cells at -80°C, makes it easier to transport these cells to the orbiting lab, providing more flexibility in launch and operations schedules.

31 May 2021

Convergence science are needed to prevent plant disease outbreaks

Plant diseases don't stop at national borders and miles of oceans don't prevent their spread, either. That's why plant disease surveillance, improved detection systems, and global predictive disease modeling are necessary to mitigate future disease outbreaks and protect the global food supply, according to a team of researchers in a new commentary published in Proceedings of the National Academy of Sciences.

24 May 2021

Researchers identify promising treatments for late-onset Alzheimer’s disease

Scientists from The Mount Sinai Hospital and the National Center for Geriatrics and Gerontology based in Japan have recently discovered novel molecular mechanisms that drive late-onset Alzheimer’s disease (LOAD).

25 Nov 2020

Dual-chip system for monitoring heart toxicity from breast cancer drugs

Breast cancer is the most commonly occurring cancer for women around the world, and much effort has been spent in the development of therapies to treat this disease.

27 Oct 2020

Researchers uncover problems with the conventional method for growing organoids

Organoids are stem cell-based tissue surrogates that can mimic the structure and function of organs, and they have become a key component of numerous types of medical research in recent years.

1 Oct 2020

HPSC-based disease modeling can help treat heart diseases

A team of researchers has reported a article relating to human pluripotent stem cell-derived cardiomyocytes in the modeling and repair of heart disease.

11 Aug 2020

COVID-19 virus can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

1 Jul 2020

Human stem cell models reveal neurodegeneration in glaucoma

Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.

12 Jun 2020

Beta Cells From Stem Cells

The loss of insulin-secreting beta cells leads to type 1 diabetes. Islet cell transplantation has the potential to cure diabetes, but donors are rare.

28 Apr 2020

UMSOM researchers uncover mechanism to explain role of genetic mutations in kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

6 Apr 2020