Efficacy News and Research

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Mitochondrial Transfer Uncovered as Key Player in Cancer Immune Evasion

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

12 Feb 2025

BioMed X and Merck Partnership Makes Significant Strides in Understanding ecDNA Biology

German independent research institute BioMed X announces the successful completion of its oncology research project in partnership with Merck. The data generated by this project has been acquired by Merck for further development, potentially leading to new therapeutic approaches in precision oncology.

10 Feb 2025

New Synthesis Method Makes Ibogaine More Accessible for Research

Ibogaine, a psychoactive compound derived from plants, has garnered attention for its anti-addictive and anti-depressant properties.

7 Feb 2025

New CRISPR Tool Reveals Key Lymphoma Genes

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

7 Feb 2025

Nutrient Starvation Impedes Antibiotic Efficacy in Salmonella Infections

A new study from the University of Basel, published in Nature, challenges the conventional understanding of antibiotic treatment failure. Rather than attributing such failures to a small population of highly resistant bacteria, the research suggests a different explanation.

6 Feb 2025

Researchers Uncover CAR Molecule Transfer Mechanism

Engineered immune cells known as CAR-T cells are utilized in cancer treatment. Researchers at Uppsala University have recently identified that CAR molecules can be transferred from CAR-T cells to other T cells within the tumor microenvironment.

4 Feb 2025

Studies Reveal Early Resistance to Newly Developed Antibiotics

Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics. Two recent studies, published just days apart in Nature Microbiology and Science Translational Medicine found that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.

31 Jan 2025

Temperature-Sensitive Protein Enables Non-Invasive Control of Cellular Behavior

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

30 Jan 2025

New Lipids Dramatically Improve Gene Therapy and Vaccine Delivery

Every time a shuttle docks with the International Space Station (ISS), a precise and intricate process takes place between the shuttle’s docking system and its counterpart on the station

29 Jan 2025

Peptides Boost Anti-Tumor Activity of Drugs

A team of scientists has created a ground-breaking method for improving drug formulations by employing specifically engineered peptides.

27 Jan 2025

Can Mechanochemistry Provide Greener Options for Pharmaceutical Manufacturing?

This study reveals efficient synthesis of ibuprofen:nicotinamide co-crystals via mechanochemistry, highlighting sustainability in pharmaceutical production.

27 Jan 2025

New Method for Engineering GPCRs Opens Pathways for Advanced Drug Development

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions.

24 Jan 2025

AI-designed proteins revolutionize snakebite treatment

Research highlights the potential of deep learning in creating proteins that neutralize snake venom, offering new solutions for neglected tropical diseases.

24 Jan 2025

Gene-Edited Bacteria Increases Nitrogen Fixation in Corn

If corn ever felt envious of soybean’s relationship with nitrogen-fixing bacteria, advancements in gene editing may one day level the playing field.

17 Jan 2025

AI-Powered Platform for Designing Novel Protein Interactions

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for biomedicine by using deep learning to create new proteins that bind to complexes involving other small molecules, such as hormones or medications.

17 Jan 2025

New Study Offers Hope for Safer, More Effective Snakebite Treatment

Last year’s Chemistry Nobel Laureate published a new study in Nature that could revolutionize the way snakebite is treated.

16 Jan 2025

Study Reveals T Cells as Key Players in Complete Viral Infection Control

Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that T cells-white blood cells that can destroy harmful pathogens-can completely prevent viral infection, to an extent previously thought only possible due to neutralizing antibodies.

13 Jan 2025