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FAM110A's Dual Role: Orchestrating Microtubule-Actin Interactions in Mitosis

An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.

17 Jul 2024

Study Offers Insights Genetic Variants Influencing Pubertal Timing

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

2 Jul 2024

Determining Sex in Ants

Researchers at the universities of Mainz and Lausanne have identified a noncoding gene as the deciding factor in determining sex in Argentine ants.

From University of Mainz 7 Jun 2024

Genetic Clues Unveil New Insights into Restless Leg Syndrome

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults.

6 Jun 2024

New Computational Method STew Bridges Gap Between Gene Expression and Spatial Biology

In disease research, it's important to know gene expression and where in a tissue the expression is happening, but marrying the two sets of information can be challenging.

5 Jun 2024

CRISPR Screening Reveals Peptide in Human RNA Regulating Inflammation

UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus.

27 May 2024

Comprehensive Analysis of Gene-Isoform Variation Unlocks Secrets of Brain Development

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

24 May 2024

Upgraded Nipponbare Genome Assembly Paves the Way for Enhanced Rice Research

A research team has achieved a groundbreaking improvement in the haplotype-resolved genome sequence of the japonica rice cultivar Nipponbare.

21 May 2024

Study Reveals How tRNA Modification Influences Malaria Drug Resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites’ ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

20 May 2024

Sex-Specific Effects of Germline Regulation on Longevity and Repair in Vertebrates

The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates.

17 May 2024

Revealing the Genetic Mechanisms Driving SARS-CoV-2 Variants

The SARS-CoV-2 virus, responsible for COVID-19, exhibits a troubling tendency to produce variants frequently.

23 Apr 2024

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

13 Apr 2024

Unraveling the Molecular Mechanisms of DNA Entanglement Resolution

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Landmark Achievement: Completion of First Sugarcane Genome Sequencing

The first comprehensive reference genome for 'R570', a widely cultivated modern sugarcane hybrid, has been completed in a landmark advancement for agricultural biotechnology.

28 Mar 2024

$1.65 Million Grant Awarded for Advancing Therapeutic RNA Design

A team led by Dr. Samie Jaffrey, the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medicine, has been awarded a three-year, $1.65 million grant for RNA research under a biotechnology-development program run by the U.S. National Science Foundation.

22 Mar 2024

Soil Bacteria Gene Discovery Offers Hope for Bioremediation Efforts

Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found.

19 Mar 2024

Protein Fragments Uncover New Extremophiles, Aiding Alien Life Search

Microorganisms with perfect adaptations can survive in harsh settings, such as deep-sea tunnels and mountain peaks.

18 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

The Surprising Impact of Chaperone Proteins on Multicellular Evolution

In a recent study, scientists used an instrument known as “experimental evolution” under the direction of researchers from the University of Helsinki and the Georgia Institute of Technology.

11 Mar 2024

Unraveling Cacao's Past: Ancient Trade Routes and Genetic Diversity Explored

The cacao tree (Theobroma cacao), whose beans (cocoa) are used to make products including chocolate, liquor and cocoa butter, may have spread from the Amazon basin to the other regions of South and Central America at least 5,000 years ago via trade routes, suggests a paper published in Scientific Reports.

11 Mar 2024