Liver Cancer News and Research

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Liver cancer is more common in older people. Over half of people newly diagnosed with liver cancer are age 65 and over. Liver cancer is more common in men than in women. Liver cancer rates are highest among Asians and Pacific Islanders, most likely because of higher prevalence of viral Hepatitis infection. Liver cancer rates are lower among whites than Blacks or Asians and Pacific Islanders. At this time, we do not know exactly what causes cancer of the liver. There are several different types of liver cancer. The most common type is associated with long-term excessive alcoholic beverage use, scarring of the liver (cirrhosis), and Hepatitis B virus or Hepatitis C virus infection. Long-term use of anabolic steroids can also increase the risk of getting liver cancer. Smoking is also believed to increase the risk of getting liver cancer.

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

4 May 2023

CRISPR-Cas9 Driven Gene-Editing Tool Models Liver Cancer Tumor Subtypes

Mutations in human genes can cause serious issues, such as colon or liver cancer. However, cancer is a very complex condition. Mutations in the same genes can result in distinct kinds of cancers in different persons.

11 Apr 2023

Integrated-Gut-Liver-on-a-Chip can Improve Understanding of Non-Alcoholic Fatty Liver Disease

A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs.

10 Apr 2023

Highlighting a potential sex‐specific precision immunotherapy strategy

Immunotherapy is an effective form of treatment for various types of cancer. However, its effect on pancreatic cancer is restricted and varies between men and women. Karolinska Institutet scientists have observed a possible explanation for this gender difference.

17 Mar 2023

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023

Molecular staple: The DNA repair mechanism impeding cancer treatment

Due to the continuous cellular activity, malfunctions frequently occur, making error-correcting systems crucial for cells. However, it serves the cancer cells’ best interests to cause errors when it comes to destroying them.

30 Jan 2023

Researchers create a tool to predict the effects of different diets on cancerous and healthy cells

A tool was developed by researchers to forecast the impact of various dietary plans on both cancerous and healthy cells.

30 Jan 2023

Research team outlines three-step technique that lets human body defend against Hep B

A team from the University of Geneva (UNIGE) has unraveled the precise operation of this defensive mechanism after finding a crucial protein complex that is active when our body is infected by the virus, paving the path for novel treatment targets.

5 Oct 2022

The strategy used by metastatic cancer cells to invade the liver identified

The alternative pathway for liver metastasis has been revealed by a team of researchers.

5 Oct 2022

Research highlights the new genetic variations and pediatric NAFLD severity

A multidisciplinary group of researchers at the University of California San Diego School of Medicine have advanced investigations into the genetic causes of NAFLD in children.

1 Jul 2022

Lipid nanoparticles successfully stopped the emergence and development of tumors cells, a new study reveals

UT Southwestern researchers have developed nanoparticles that can penetrate the physical barriers that surround tumors and reach cancer cells.

27 Jun 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

A new study has led to the discovery that the Hippo signaling effector YAP1 is a master controller of Nodal signaling in hESCs for a process crucial to human development.

14 Feb 2022

Coffee found to have a stimulating effect on some digestive processes

A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.

19 Jan 2022

Novel peptide vaccine alleviates conditions of dyslipidemia

Professor Yuichi Oike and his group of researchers recently produced a peptide vaccine that mitigates conditions of dyslipidemia.

17 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

8 Dec 2021