Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

DNA Methylation Governs Citric Acid Production in Lemons

Lemons owe their signature tang to citric acid, yet the molecular mechanisms governing its accumulation have long remained a mystery.

12 Feb 2025

Study Reveals How Gut Bacteria Influence Brain Protein Modifications

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease.

11 Feb 2025

Research Sheds Light on How Obesity Affects Gene Expression in Fat Cells

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

11 Feb 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

First Cell Atlas of Focal Cortical Dysplasia Offers New Insights for Treatment

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy.

31 Jan 2025

New Protein Structures Could Lead to Better Treatments for Transthyretin Amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

Unique Genetic Signature Predicts Bacteria's Potential to Develop Antibiotic Resistance

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually.

29 Jan 2025

Indigenous Management Practices Found to Boost Genetic Diversity of Brazil Nut Trees

Researchers from the German Max Planck Institutes of Geoanthropology and Biology Tübingen use genomic data to study the decline in genetic diversity in the Amazon Basin, particularly in Brazil Nut trees.

27 Jan 2025

New Technique Unifies Protein Size Measurements to Predict Aggregation Risk

Proteins are necessary for many bodily processes. Numerous physiological functions and activities are carried out by thousands of distinct proteins.

21 Jan 2025

EMBL and ELLIS Forge Strategic Partnership to Advance AI in Life Sciences

A new collaborative agreement aims to help position Europe at the forefront of AI-driven advancements in life sciences research.

15 Jan 2025

Understanding RapA's Function in E. coli R-loop Control

From a genetic perspective, it is the worst-case scenario for a bacterium: during transcription, freshly created RNA adheres to its DNA template to form a three-stranded structure called an R-loop.

15 Jan 2025

Research Shows How Sleep Clears Brain Waste

A good night's sleep does more than just help you feel rested-it might literally clear your mind. A new study published January 8 in the Cell Press journal Cell shows how deep sleep may wash away waste buildup in the brain during waking hours, an essential process for maintaining brain health.

10 Jan 2025

Illuminating RNA Function with Innovative Bioluminescent Probes

The molecule that reads the genetic data contained in DNA is called RNA. Researchers at the University of California, Irvine have found a method to tag RNA with a glowing bioluminescent molecule, which enables them to track RNA in real time as it travels throughout the body.

10 Jan 2025

Weak Molecular Interactions Trigger Autophagy in Cells

Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks.

8 Jan 2025

New Mechanism Revealed for Immune Response to DNA Damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

7 Jan 2025

New Synthetic Biology Tool Improves Genetic Circuit Integration and Functionality

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

23 Dec 2024

PlantRNA-FM: Bridging the Gap Between RNA Structure and Function

With PlantRNA-FM, researchers can systematically analyze plant RNA, uncovering functional motifs that play key roles in gene expression and stress responses.

23 Dec 2024

Chaperone Proteins Unveil Their Role in Neurotransmission

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating diseases such as Alzheimer's and Parkinson's along with many others, can occur.

19 Dec 2024

A revolutionary antibody approach to fight cancer by restoring cellular fitness

Ovarian cancer cells exploit cell competition by altering Flower protein isoforms in stromal cells, promoting tumor survival and potential therapeutic targets.

18 Dec 2024

Researchers Map Influenza Virus RNA Protective Coat at Atomic Level

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of eight RNA molecules.

17 Dec 2024