Musculoskeletal News and Research

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Loss of mitochondrial respiration alters mechanical properties of the cartilage

A group of researchers headed by Professor Dr Bent Brachvogel, Head of Experimental Neonatology at the Faculty of Medicine and University Hospital Cologne, have identified regulatory mechanisms of tissue organization which were earlier unknown.

8 Oct 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

Scientists isolate monoclonal antibodies against alphaviruses

A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.

From Vanderbilt University 24 Aug 2021

Muscle protein tied to physical fitness in youth and age-associated diseases

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

9 Aug 2021

New nanobodies could fight against SARS-CoV-2 variants

Looking for a new strategy in the long-running battle against the SARS-CoV-2 virus, researchers have developed nanobodies.

23 Jun 2021

Protein in skeletal muscular system may play a key role in the body's fight or flight response

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.

26 Apr 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Regenerating bone marrow after chemotherapy

In this interview, AZoLifeSciences speaks to Professor Masaru Ishii about his latest research that investigated how bone marrow regenerates after chemotherapy.

From Osaka University 10 Mar 2021

Study may lead to new approaches to protect older individuals from viruses

A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows.

16 Dec 2020

Ultra-processed foods increase risk of muscle pain

A research team from the Universitat Rovira i Virgili (Tarragona - Spain) has observed that following a diet rich in fats and sugars from ultra-processed foods (such as sweet rolls and pastries) for a six-week period increases the number of inflammatory molecules in the organism, which increases the excitability of the muscle nerves.

16 Nov 2020

Dried plum diet prevents bone loss associated with spinal cord injury

Findings from a new study among mice show a diet high in dried plum (prunes) completely prevents bone loss associated with spinal cord injury (SCI), while also restoring some of the bone lost following SCI.

7 Oct 2020

Novel genetic measure could improve screening for osteoporosis

An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility.

22 Jul 2020

Functional bone imaging technique reveals the progression of knee osteoarthritis

A new approach to functional bone imaging has established that bone metabolism is abnormally elevated in patients with knee osteoarthritis.

14 Jul 2020

New molecular imaging method can identify the location of pain generators

A new molecular imaging approach utilizing 18F-FDG positron emission tomography (PET) and magnetic resonance imaging (MRI) can precisely identify the location of pain generators in chronic pain sufferers, often precipitating a new management plan for patients.

14 Jul 2020

Softening cell's nucleus can help the body to efficiently repair injuries

By softening a cell's nucleus so that it can squeeze its way through dense connective tissues, a group of researchers believe they've demonstrated a new way to help the body efficiently repair injuries.

23 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020

Gene therapy builds muscle mass, reduces fat in mice

Exercise and physical therapy often are recommended to help people who have arthritis. Both can strengthen muscle - a benefit that also can reduce joint pain.

12 May 2020