Nucleotides News and Research

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Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023

Simplifying Bacterial Genetic Material Detection

Scientists have devised an approach for swiftly, inexpensively, and with greater precision, identifying bacteria. This advancement holds the potential for minimizing the reliance on antibiotics.

29 Nov 2023

A Novel Technique for Ribonucleotide Quantification

Scientists at the Folkhälsan Research Center have devised a novel technique enabling the straightforward quantification of ribonucleotides in small tissue and cell samples within a standard laboratory setting, without the need for specialized equipment.

28 Nov 2023

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

Scientists at Oak Ridge National Laboratory used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

10 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

DNA-Origami Nanoengine Performing Pulsing Movements

An international team of scientists has just invented a revolutionary form of DNA nano-engine.

20 Oct 2023

New Insights Into Lactate Transporters and Their Therapeutic Potential

Researchers from the Giulio Superti-Furga Lab at CeMM, the Austrian Academy of Sciences’ Research Center for Molecular Medicine, have developed a new technique for identifying specific inhibitors of a lactate transporter linked to cancer and other diseases.

31 Jul 2023

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

The amount of data generated by scientists today is massive, thanks to the falling costs of sequencing technology and the increasing amount of available computing power.

22 Jun 2023

New Method Provides Near-Perfect Control Over the Manipulation of Individual Molecules

Aleksandra Radenovic, Head of the School of Engineering’s Laboratory of Nanoscale Biology, has spent years working to enhance nanopore technology, which primarily involves a molecule like DNA through a tiny pore in a membrane to quantify an ionic current.

20 Jun 2023

Heat-Damaged DNA in Food Linked to Possible Genetic Risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

14 Jun 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Stimulating Cell DNA Repair Processes to Combat the Root Cause of Autism Spectrum Disorders

A new treatment option has been discovered for fragile X syndrome, which is the most common genetic cause of autism spectrum disorders and is defined by a hereditary repetition of certain nucleotides in the DNA sequence of the FMR1 gene. Researchers at Massachusetts General Hospital (MGH) carried out the study, which was published in the journal Cell.

22 May 2023

New Genetic Mutations Linked to Canine Bladder Cancers Identified

Researchers have identified new genetic mutations linked to a subset of canine bladder cancers. Their findings have implications both for early cancer detection and for targeted treatments in dogs and humans.

26 Apr 2023

A Rapid Method for the Quantitative Detection of miRNA

Researchers investigating the growth of a roundworm discovered a tiny RNA molecule that controlled the expression of specific genes in the early 1990s. This resulted in the discovery of microRNAs (miRNAs), which are now known to exist in all forms of life. These molecules, it turns out, play vital functions in a variety of biological processes.

26 Apr 2023

Nucleotides News and Research

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

Simplifying Bacterial Genetic Material Detection

A Novel Technique for Ribonucleotide Quantification

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

DNA-Origami Nanoengine Performing Pulsing Movements

New Insights Into Lactate Transporters and Their Therapeutic Potential

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

New Method Provides Near-Perfect Control Over the Manipulation of Individual Molecules

Heat-Damaged DNA in Food Linked to Possible Genetic Risks

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

Stimulating Cell DNA Repair Processes to Combat the Root Cause of Autism Spectrum Disorders

New Genetic Mutations Linked to Canine Bladder Cancers Identified

A Rapid Method for the Quantitative Detection of miRNA

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Novel web-based tool deoptimizes genetic sequences based on different codon usage

New framework to identify possible viral hazards to human health

Researchers uncover how DNA double-stranded breaks are repaired

Improved efficacy of advanced genome editing with machine learning

Pancreatic islet microexons play key role in islet function and glucose homeostasis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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