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Unusual partners aid new blood vessel development

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

9 Mar 2022

Mortality of newborns on ECMO linked with red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

15 Feb 2022

Hematopoietic stem cells play key focus of stem-cell-based medical research

According to a recent study, a protein that controls how DNA is wrapped within chromosomes plays a key role in the proper functioning of blood stem cells.

2 Feb 2022

Biochemical signals sent from cell to cell play a key role in deciding their fate

Scientists have found a way to prove that biochemical signals sent from cell to cell play an important role in determining how those cells develop.

24 Dec 2021

Scientists identify novel nairovirus associated with acute febrile illness in Japan

A previously unknown virus that can infect humans and cause disease has been identified by scientists in Japan.

5 Oct 2021

Pushing organ-on-a-chip microdevices to new levels to improve ovarian cancer treatment

In the evolving field of cancer biology and treatment, innovations in organ-on-a-chip microdevices allow researchers to discover more about the disease outside the human body.

26 Jul 2021

New fluorescent probe that can discriminate B lymphocytes over T lymphocytes

Human blood contains several different components, including plasma, red blood cells (RBCs), white blood cells (WBCs), and platelets.

15 Apr 2021

Regenerating bone marrow after chemotherapy

In this interview, AZoLifeSciences speaks to Professor Masaru Ishii about his latest research that investigated how bone marrow regenerates after chemotherapy.

From Osaka University 10 Mar 2021

Study identifies molecular mechanism by which HSPCs recover after chemotherapy-induced injury

Chemotherapy has a damaging effect on hematopoietic stem and progenitor cells (HSPCs) in bone marrow. However, once chemotherapy ends, HSPCs regenerate, a process that has remained unknown--until now.

From Osaka University 8 Mar 2021

Study shows how stem cell niche maintain their self-renewal capacity

A typical trait of all stem cells is their potential to renew on their own; however, scientists are unsure about how this ability is sustaining throughout life.

28 Jan 2021

Study shows how specific gene mutations cause different types of diseases

Renowned cancer experts have resolved a query of how different types of mutations in a single gene are responsible for causing various types of diseases.

15 Jan 2021

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

Using 3D mapping techniques to unravel mystery of blood stem cells

Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughout our life by looking at vast, uncharted regions of our genetic material that hold important clues to subtle biological changes in these cells.

26 Nov 2020

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Study probes mechanism by which COVID-19 distribution in the body damages erythrocytes

Experts have investigated the mechanisms of COVID-19 inside-the-body distribution related to the damage of erythrocytes.

2 Nov 2020

New material could contribute to climate protection and sustainable industrial production

Chemists at the University of Bayreuth have developed a material that could well make an important contribution to climate protection and sustainable industrial production.

21 Oct 2020

Sticky DNA webs may cause tissue damage linked to severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published on September 14 in the Journal of Experimental Medicine (JEM).

15 Sep 2020

Organ-on-a-chip research explores link between ovarian cancer and blood cells

Recent discoveries made by researchers at Texas A&M University could change the way ovarian cancer is understood and treated.

17 Aug 2020

Epigenetics key to daily production of 10 billion blood cells without mistakes

Just one in 2,000 bone marrow cells are hematopoietic stem cells (HSC), but these are the source of the ten billion blood cells humans make every day.

6 Aug 2020

Scientist receives DoD grant to develop freeze-dried synthetic platelets

A Case Western Reserve University scientist, who has for more than a decade pioneered research into synthetic platelet substitutes, has been awarded a $3.8 million grant by the U.S. Department of Defense (DOD) to develop freeze-dried artificial platelets that can treat bleeding in wounded soldiers in the battlefield before they can be taken to a hospital.

22 Jul 2020