Programmed Cell Death News and Research

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Novel Bacterial Protein can Prolong Cell Longevity by Acting Directly on Mitochondria

Researchers at the University of São Paulo (USP) in Brazil, partnering with colleagues in Australia, have identified a novel bacterial protein that can keep human cells healthy even when the cells have a heavy bacterial burden.

10 Nov 2023

Hair Follicle Regression may be Driven by Cell-to-Cell Apoptosis

A new research paper was published in Oncotarget's Volume 14 on October 19, 2023, entitled, "Apoptotic cells may drive cell death in hair follicles during their regression cycle."

24 Oct 2023

New Findings Suggest Endosymbiotic Origin of Apoptosis

Apoptosis, frequently described as programmed cell death, is a fundamental mechanism essential for the growth and development of multicellular organisms.

13 Oct 2023

Titanium Micro-Spikes Skewer Resistant Superbugs

A new study suggests rough surfaces inspired by the bacteria-killing spikes on insect wings may be more effective at combatting drug-resistant superbugs, including fungus, than previously understood.

30 Aug 2023

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

29 Jun 2023

Cells with “Jumping Genes” Self-Destruct in the Early Stages of Development

A previously unknown type of cell that self-destructs within days of forming as part of a quality control procedure to protect the growing fetus has been found by researchers studying gene activity data of the early human embryo.

21 Jun 2023

Scientists Discover New Embryonic Cell Type that Self-Destructs to Protect the Developing Embryo

Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell which self-destructs within days of forming, as part of a quality control process to protect the developing foetus.

21 Jun 2023

Researchers Elucidate the Exact Mechanism of Cell Death

24 May 2023

New Insights into the Final Step of Cell Death

Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers at the University of Basel have now been able to elucidate the exact mechanism at the atomic level. They have published their results in Nature.

23 May 2023

Discovering Novel Senolytic Compounds with the Power of Artificial Intelligence

A new publication in the May issue of Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, demonstrates the power of artificial intelligence (AI) to discover novel senolytic compounds, a class of small molecules under intense study for their ability to suppress age-related processes such as fibrosis, inflammation and cancer.

8 May 2023

Blocking Necroptosis Could Lead to the Inhibition of Cancer Metastasis

A new editorial paper was published in Oncotarget's Volume 14 on April 10, 2023, entitled, "Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity."

25 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Researchers discover murderous survival strategy of yeast

Yeast is not the simple single-celled microorganism we once thought, but a competitive killer. When starved of glucose, yeast releases a toxin that will poison other microorganisms that have entered its surrounding habitat, even its own clones.

8 Nov 2022

New CRISPR RNA-guided Caspases could lead to promising antiviral and tissue engineering tools

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

26 Aug 2022

Researchers determine a novel antiviral technique to combat bacteria

Bacteria use a wide range of defense strategies to combat viral infection, and some of these systems have resulted in game-changing technologies like CRISPR-based gene editing.

From Massachusetts Institute of Technology (MIT) 15 Aug 2022

Study provides guidelines on how to design safer CRISPR reagents

The 2020 Nobel Prize in Chemistry was awarded to Jennifer A. Doudna and Emmanuelle Charpentier for developing the widely utilized and incredibly precise genome editing method known as CRISPR/Cas9

11 Aug 2022

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Aging and age-related diseases present a complex challenge to biomedical researchers.

20 Jul 2022

Researchers discover a mechanism by which the protein DELE1 detects organelle stress

Researchers have long speculated an association between disorders in mitochondria, tiny organelles inside the cell, and the aging process and age-related illnesses.

11 Apr 2022

Study shows that mechanical stress help cancer cells metastasize

A recent study shows that compressing cancer cells through tight spaces makes them more violent and helps them avoid cell death.

9 Mar 2022