Protein Aggregation News and Research

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Bacteria-derived curli amyloid fibril promotes neurodegeneration in the host

Increasing evidence points to the fact that gut microbiota performs a vital role in regulating the advancement of neurodegenerative diseases like Alzheimer’s.

9 Sep 2021

Researchers develop a novel process to desalinate whey

Scientists reveal that the increased salt content of whey makes it one of the most polluting byproducts in the food processing industry.

7 Sep 2021

Nanobody mapping using NMR proves a promising alternative for therapeutic use

Researchers used NMR techniques to determine the structure of a nanobody, facilitating a better understanding of how the protein fights against diseases.

6 Jul 2021

First real-time observation of DNA-histone interactions

The genetic material of most organisms is carried by DNA, a complex organic molecule. DNA is very long -- for humans, the molecule is estimated to be about 2 m in length.

2 Jun 2021

Study: Sous vide cooking increases the digestibility of beef protein

Once used to prepare cuisine in only the finest restaurants, sous vide is now making its way into home chefs' kitchens. French for "under vacuum," the technique involves vacuum sealing food in a plastic pouch and then slowly cooking it in warm water.

10 Dec 2020

Plant amyloids could improve nutritional value of plant seeds, reduce allergenicity of legume seeds

Thanks to this work, as the journal Trends in Plant Science recently noted, it is now known that functional amyloids serve biological functions in representatives of almost all large groups of living organisms: bacteria, archaea, animals, fungi, and plants.

3 Dec 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

Postnova Analytics' 2D FFF system opens up completely new ways for separations

Postnova Analytics powerful EAF4 technology combines the principle of Electrical and Asymmetrical Flow Field-Flow Fractionation in just one system.

From Postnova Analytics 17 Sep 2020

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

Chinese researchers recently discovered a protein quality control mechanism called "reubiquitination".

9 Jul 2020

Researchers identify osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Protein modification may cause long-term consequences

Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.

20 May 2020

Metals can affect the formation of harmful misfolded peptide clusters in various diseases

Revealing the interactions between metal ions and peptides in the body could help develop enhanced treatments for Alzheimer’s diabetes, and other diseases.

14 Apr 2020