Schizophrenia News and Research

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Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

How Seba's Short-Tailed Bats Navigate Their Acoustic World

The world of bats is full of sounds. They utilize vocalizations for both navigation and communication with their conspecifics. For the latter, they produce ultrasonic noises that reverberate and allow them to form a mental "image" of their environment

26 Feb 2024

Ancient DNA Reveals Reason for High Multiple Sclerosis and Alzheimer’s Rates in Europe

Researchers have created the world’s largest ancient human gene bank by analysing the bones and teeth of almost 5,000 humans who lived across western Europe and Asia up to 34,000 years ago.

10 Jan 2024

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

A new study published in Nature Cell Biology by Mark Alkema, PhD, professor of neurobiology, establishes an important molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.

5 Jan 2024

Unlocking the Mysteries of Fetal Brain Development

Cheryl Rosenfeld has dedicated three decades to investigating the transmission of biological information from mothers to babies during pregnancy.

6 Dec 2023

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023

New Method That Genetically Modifies Individual Cells in Animals

Researchers at ETH Zurich have created a technique that enables them to genetically alter every animal cell in a unique way.

22 Sep 2023

Genetic Risk of Depression Linked to Increased Risk of Other Psychiatric Disorders

Recent research reveals that people who are hospitalized for depression are at an increased risk of developing conditions like substance abuse, bipolar disorder, schizophrenia, and anxiety, depending on their genetic predisposition to the individual disorder.

30 Aug 2023

Schizophrenia-Linked Chromosome Deletion Affects Mitochondria

Investigators are learning more about how schizophrenia develops by investigating the most powerful known genetic risk factor.

22 Aug 2023

New Class of Brain Inhibitory Neurons May Contribute to Autism and Schizophrenia

A University of California, Irvine-led team of researchers working at the Center for Neural Circuit Mapping find links between brain disorders and dysfunction of newly identified inhibitory brain cell types.

26 Jul 2023

Cryo-EM Reveals Structure of GABA Transporter

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

7 Jul 2023

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

According to new research published in Nature Biotechnology, artificial intelligence can predict on- and off-target behavior of CRISPR tools that target RNA rather than DNA.

5 Jul 2023

Neurotransmitter Receptor Patterns Define Key Organizational Principles in the Brain

Receptor patterns define key organizational principles in the brain, scientists have discovered.

20 Jun 2023

Scientists Discover the Mechanisms of Synaptic Pruning in Brain Development

Researchers at Kyushu University have uncovered the mechanisms of a fundamental yet critically under-looked phase in brain development: synaptic pruning.

8 Jun 2023

CSHL Scientists Flip the Script on Autism Genetics

Cold Spring Harbor Laboratory researchers have flipped the script on autism spectrum disorder (ASD) genetics.

23 May 2023

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Markers Indicating Early Signs of Schizophrenia Identified

For the first time, a global study group headed by investigators at Virginia Commonwealth University has found markers that might point out early if a person is susceptible to schizophrenia in the early stage itself.

28 Apr 2023

Understanding the Origins of Human Disease Using the Power of Evolutionary Genomics

Hundreds of scientific studies have been conducted over the years to find the genes underlying common human traits, from eye color to intelligence and physical and mental illnesses.

28 Apr 2023

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease?

28 Apr 2023

Key Mediator of Anhedonia-Like Behavior Identified

Researchers uncovered a stress-regulated gene that is important in the relationship between chronic stress and typical depressed behavior in mice.

10 Apr 2023

Study investigates schizophrenia risk across African ancestry

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism. Led by the Icahn School of Medicine at Mount Sinai, the multi-center study further demonstrated that the schizophrenia risk conferred by these rare damaging variants is conserved across ethnicities. The study may also point to new therapeutics.

14 Mar 2023

Schizophrenia News and Research

How Seba's Short-Tailed Bats Navigate Their Acoustic World

Ancient DNA Reveals Reason for High Multiple Sclerosis and Alzheimer’s Rates in Europe

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

Unlocking the Mysteries of Fetal Brain Development

Uncovering New Insights Into Primate Brain Evolution

New Method That Genetically Modifies Individual Cells in Animals

Genetic Risk of Depression Linked to Increased Risk of Other Psychiatric Disorders

Schizophrenia-Linked Chromosome Deletion Affects Mitochondria

New Class of Brain Inhibitory Neurons May Contribute to Autism and Schizophrenia

Cryo-EM Reveals Structure of GABA Transporter

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

Neurotransmitter Receptor Patterns Define Key Organizational Principles in the Brain

Scientists Discover the Mechanisms of Synaptic Pruning in Brain Development

CSHL Scientists Flip the Script on Autism Genetics

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

Markers Indicating Early Signs of Schizophrenia Identified

Understanding the Origins of Human Disease Using the Power of Evolutionary Genomics

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

Key Mediator of Anhedonia-Like Behavior Identified

Study investigates schizophrenia risk across African ancestry

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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