CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Researchers reveal the dual function of a zinc finger protein

Human genome mapping was followed by rapid scientific advancements that showed the astonishingly complex world of genetics.

29 Oct 2021

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Ghent University’s concentrated on a technique for the safe engineering of therapeutic cells with photothermal nanofibers for the past decade.

26 Oct 2021

Study investigates the role of essential genes in acetic acid tolerance

Saccharomyces cerevisiae, also known as Baker’s yeast, is industrially utilized for the production of different biochemicals.

21 Oct 2021

Experts explain left–right asymmetry development in the embryo

Research on the development of symmetry in mice embryos is anticipated to provide a deeper understanding of the causes of disease.

21 Oct 2021

Junk DNA' plays a crucial role in early embryonic development in all mammals, study shows

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Study explores the effects of epigenetic editing in various tumor settings

Recent research reports that the appropriate functioning of this mechanism is essential for tissue homeostasis and cell fate determination.

13 Oct 2021

Does the Future of Farming Involve the Gene Editing of Farm Animals?

In this interview, AZoLifeSciences speaks to the RSPCA about the future of farming, and whether it involves gene-edited farm animals.

8 Oct 2021

Study offers important insights into how circadian clocks function at the subcellular level

Almost every living thing on Earth-;from bacteria to plants to people-;have a circadian rhythm, the biological clock that controls both physiology and behavior of organisms over a 24-hour period.

1 Oct 2021

Study unravels factors involved in risiRNA generation

A team of scientists disclosed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism.

1 Oct 2021

Experts unravel inner workings of cell receptors involved in various diseases

Scientists revealed the operational mechanism of possible drug targets for numerous diseases like rheumatoid arthritis, cancer, and even COVID-19.

1 Oct 2021

Researchers explore the regulation of suberin in Arabidopsis thaliana

Plants modify the permeability of their roots to adapt to their nutritional needs. This takes place through the degradation or production of suberin.

27 Sep 2021

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

17 Sep 2021

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

New scalable genetic control system to restrain disease-spreading mosquitoes

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

From UC San Diego 13 Sep 2021

Study unearths previously unknown role of CTCF, the transcription regulator

Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.

9 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Think of cells as tiny factories: within their walls they have both the machinery to make products such as proteins, and the mechanisms for maintenance to keep processes running smoothly.

31 Aug 2021