Immune Response News and Research

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Anti-idiotype antibodies may explain the long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection.

From The University of California, Davis 26 Nov 2021

Study analyzes connections between COVID-19 severity and gene expression

Recent research reveals how genetic variations associated with severe cases of COVID-19 impact the immune cells.

25 Nov 2021

Researchers expand understanding of how T cells recognize infections or disease

T cells communicate with other cells in the body in search of infections or diseases. This crosstalk relies on specialized receptors known as T cell receptors that recognize foreign molecular fragments from an infection or cancer that are presented for detection by particular molecules called major histocompatibility complex (MHC) or MHC-like.

23 Nov 2021

MIT researchers identify a way to indirectly activate T cells to fight tumors

Under the right circumstances, the body's T cells can detect and destroy cancer cells. However, in most cancer patients, T cells become disarmed once they enter the environment surrounding a tumor.

22 Nov 2021

Covid-19 vaccine-elicited immune cells persist six months after vaccination, study shows

A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes — immune system cells also known as helper T cells — produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination and are at significantly higher levels than for those who are unvaccinated.

17 Nov 2021

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered.

12 Nov 2021

Study explores mechanism by which ToBRFV tomato virus overcomes tobamovirus resistance

A new viral tomato disease that broke in the past few years has threatened tomato production across the globe.

8 Nov 2021

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

8 Nov 2021

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University of California, Davis.

From The University of California, Davis 2 Nov 2021

Research reveals how foodborne infections protect the gut's nervous system

A simple stomach bug could do a lot of damage. There are 100 million neurons scattered along the gastrointestinal tract-;directly in the line of fire-;that can be stamped out by gut infections, potentially leading to long-term GI disease.

1 Nov 2021

Study unravels unknown facts about SARS-CoV-2 infection

Around 3%–10% of the individuals infected by the SARS-CoV-2 experience moderate to severe disease.

1 Nov 2021

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

29 Oct 2021

Novel genetic biomarkers accurately predict SARS-CoV-2 infection, says study

Researchers from the University of Colorado School of Medicine identified specific genetic biomarkers that reveal who is infected with COVID-19.

29 Oct 2021

Correction of immune system's faulty timing may offer a new strategy to prevent severe COVID-19

Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response.

27 Oct 2021

Scientists reveal the importance of circadian rhythm on the immune system

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

19 Oct 2021

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers identified a greatly potent monoclonal antibody that aims at the spike protein of SARS-CoV-2.

19 Oct 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Study explores dietary supplementation with vitamin D to support cows’ immune function

Known as a crucial component in the body's ability to absorb and retain calcium, essential to processes such as the development and maintenance of healthy bones, vitamin D has also been found to play important roles in immune defense.

18 Oct 2021

Infection with measles virus activates two different immune responses

Researchers from The University of Tokyo Institute of Industrial Science have found that infection with the measles virus activates not one but two different branches of the innate immune system.

15 Oct 2021

Immune Response News and Research

Anti-idiotype antibodies may explain the long-term effects of COVID-19

Study analyzes connections between COVID-19 severity and gene expression

Researchers expand understanding of how T cells recognize infections or disease

MIT researchers identify a way to indirectly activate T cells to fight tumors

Covid-19 vaccine-elicited immune cells persist six months after vaccination, study shows

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

Study explores mechanism by which ToBRFV tomato virus overcomes tobamovirus resistance

'Rewiring' the mitochondria in macrophages can resolve inflammatory reactions

Monoclonal antibodies mitigate inflammatory consequences of SARS-CoV-2 exposure in macaques

Research reveals how foodborne infections protect the gut's nervous system

Study unravels unknown facts about SARS-CoV-2 infection

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Novel genetic biomarkers accurately predict SARS-CoV-2 infection, says study

Correction of immune system's faulty timing may offer a new strategy to prevent severe COVID-19

Scientists reveal the importance of circadian rhythm on the immune system

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Study explores dietary supplementation with vitamin D to support cows’ immune function

Infection with measles virus activates two different immune responses

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