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Researchers analyze individual cells to build an atlas of the human heart

Scientists have created a cellular and molecular map of the healthy human heart, to understand how this vital organ functions, and to shed light on what goes wrong in cardiovascular disease.

25 Sep 2020

Pesco-Mediterranean Diet May Lower Risk for Heart Disease

Dr. O'Keefe speaks to AZoLifeSciences about his latest research that investigated how the pesco-mediterranean diet may lower the risk for heart disease.

From University of Missouri-Kansas City 22 Sep 2020

Study offers insight on how muscles and fat tissue communicate to improve fitness

Why does exercise training make you more fit? It's well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood.

15 Sep 2020

Treatments targeting the gut microbiome can protect space travelers from adverse health problems

Space travelers who spend long periods of time in space can experience health problems, such as adverse effects on metabolism, and immunity.

9 Sep 2020

Study shows different cell response offers more control to muscles

Slight variations in individual muscle cell contractions enable the whole muscle to bend with more precision and control.

2 Sep 2020

Mice study shows naturally-occurring metabolite improves longevity

According to results from a study, middle-aged mice had a better “old age” when the naturally-occurring metabolite, called AKG, was added to their food.

2 Sep 2020

Study shows how two proteins interact to produce functioning barrier at tricellular contacts

Organs in animals and in humans have one thing in common: they are bounded by so-called epithelial cells. These, along with the muscle, connective, and nervous tissues, belong to the basic types of tissue.

28 Aug 2020

Study looks into safety and early outcomes of gene therapy for spinal muscular atrophy

In May 2019, the U.S. Food and Drug Administration (FDA) approved a gene replacement therapy for the inherited, progressive neuromuscular disease 5q-linked spinal muscular atrophy (SMA).

26 Aug 2020

Study examines the impact of low-carb, high-fat diet in older people

A new study, published in Nutrition and Metabolism, from researchers with the University of Alabama at Birmingham's Nutrition Obesity Research Center observed improvements in body composition, fat distribution and metabolic health in response to an eight-week, very low-carbohydrate diet.

21 Aug 2020

Study sheds light on inner workings of the human heart

Researchers have investigated the function of a complex mesh of muscle fibers that line the inner surface of the heart.

20 Aug 2020

Study shows age is a major risk factor for dying from COVID-19 infection

According to a study, genes that play a significant role in enabling SARS-CoV-2 to penetrate the heart cells become more active as people age.

20 Aug 2020

Shielded stem cells can improve heart healing

Ghanta, R.K., et al. (2020) Immune-modulatory alginate protects mesenchymal stem cells for sustained delivery of reparative factors to ischemic myocardium. Biomaterials Science. doi.org/10.1039/D0BM00855A.

19 Aug 2020

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

Scientists have developed a new, multipurpose probe that is capable of detecting the programmed destruction of faulty mitochondria with pinpoint precision.

17 Aug 2020

Researchers identify a new gene to treat multiple sclerosis

Multiple sclerosis, or MS, is a disease that affects the central nervous system and can eventually lead to muscle tremors and thus loss of balance.

17 Aug 2020

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

A new cell-based gene therapy approach to correct hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

29 Jul 2020

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Analyses of lung fluid cells from COVID-19 patients conducted on a supercomputer point to patterns that may explain the body's response to SARS-CoV-2.

29 Jul 2020

Experimental mRNA-based vaccine protects animals against SARS-CoV-2

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

27 Jul 2020

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

24 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020