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Scientists identify new protein that may improve future chemotherapy treatment

Chemotherapy not only attacks cancer cells but also targets all cells in the human body. This is the reason why patients receiving this treatment generally experience adverse side effects, like hair loss, physical weakness, and nausea.

18 Dec 2020

New version of phototoxic protein helps control intracellular processes

Researchers have designed an improved version of a genetically encoded phototoxic synthesizer that helps regulate intracellular processes through light.

18 Dec 2020

New technology predicts efficacy of transplanted hEPCs in early stages of ischemic disease

In recent years, the number of high-risk groups for ischemic diseases such as critical limb ischemia where tissues of toe may decay is increasing due to increase in the number of people with obesity, diabetes, and hypertension which are triggered by changes in dietary habits, and consumption of smoking and alcohol.

18 Dec 2020

Researchers discover protein that may trigger lung scarring

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

18 Dec 2020

Scientists find new way to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

18 Dec 2020

Innovative gene therapy approach for regeneration of functional new neurons

Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. While decades of research have made significant progress in axonal regeneration after SCI, most of the interventions have not been translated into clinical therapies.

18 Dec 2020

Scientists identify new target to deliver anti-cancer drugs to tumor cells

With the evolution of cancer, the quest for identifying efficient treatment techniques for cancer patients has remained challenging.

17 Dec 2020

ECSIT protein can shed light on the origin of Alzheimer's disease

Researchers have found how a protein governs the behavior of proteins associated with the activity in mitochondria, which is impacted in Alzheimer's disease.

17 Dec 2020

Study may lead to new treatments for certain types of disease

Researchers at the Francis Crick Institute have found a new way to prevent some tumours from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments for certain types of the disease.

17 Dec 2020

Researchers detect new immune cells that act as major driver of breast cancer growth

Several breast cancer immunotherapies have had only minimal success in treating the aggressive forms of this disease.

17 Dec 2020

Study: Fungi have proteins that allow them to sense consumable things

According to a new study, the same proteins responsible for enabling human senses, like smell, also enable some fungi to sense things they can consume.

17 Dec 2020

Study: DOT1L enzyme is essential for humoral immune responses

Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists.

17 Dec 2020

Researchers discover genetic variants of host proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Study investigates OHC levels and transcriptome profiles in the liver of Baltic salmon

Hatchery-reared Atlantic salmon (Salmo salar) have been released to support the wild salmon stocks in the Baltic Sea for decades. During their feeding migration, salmon are exposed to organohalogen compounds (OHCs).

17 Dec 2020

Mouse stem cells converted into oocyte-like cells by just eight genes

Researchers have demonstrated that activating eight genes is enough to induce the stem cells of mice to transform into oocyte-like cells that can be fertilized.

17 Dec 2020

Biochemical methods reveal signal transduction mystery inside human pathogen

In order to adapt to the changing environment, bacteria must quickly transform extracellular information into appropriate intracellular reactions. Two component system (TCS) is the main signal transduction protein in prokaryotic cells to transform environmental stimuli into cellular responses.

16 Dec 2020

Microbes act as efficient microscopic fuel cell, shows study

By borrowing nature's blueprints for photosynthesis, Cornell University bioengineers have found a way to efficiently absorb and store large-scale, low-cost renewable energy from the sun - while sequestering atmospheric carbon dioxide to use later as a biofuel.

16 Dec 2020

Study may lead to new approaches to protect older individuals from viruses

A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows.

16 Dec 2020

New gene therapy approach can improve uterine blood flow in placental insufficiency

A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.

16 Dec 2020

Tumor's stiff-arm tactic restricts the effectiveness of checkpoint inhibitors

In a paper just published in the Journal for the Immunotherapy of Cancer (doi:10.1136/jitc-2020-001712), Dr. Herbert, Head of Discovery at InsideOutBio, asks whether cancer cells stiff-arm immune cells just like rugby players push off defenders from the other team.

16 Dec 2020