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Researchers discover promising drug candidate for treatment of brain disorders

Researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) discovered a novel chemical compound, which has the potential to became a new drug for the treatment of core symptoms of brain disorders like Down syndrome and autism.

13 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Study shows the negative impacts of cannabis use

Constant exposure to cannabis could have an adverse effect on sociability. According to studies, in certain indviduals, such exposures may result in reduced social interactions and withdrawal symptoms.

13 Jul 2020

Study: PINK1 and Parkin work together to induce selective autophagy

Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria to induce selective autophagy called mitophagy.

10 Jul 2020

Researchers discover how good gut bacteria can help reduce heart disease risk

Scientists have discovered that one of the good bacteria found in the human gut has a benefit that has remained unrecognized until now: the potential to reduce the risk for heart disease.

9 Jul 2020

New assay helps study adhesion of cells

Fluorescent tagging is a powerful way of analyzing communications between cells. This method enables the analysis of numerous cell populations.

7 Jul 2020

Study reveals malaria's secret to surviving in the blood stream

New research from the Francis Crick Institute has found how the malaria parasite protects itself from toxic compounds in red blood cells.

2 Jul 2020

In vitro cardiotoxicity screening using 3D-printed human heart tissues

Ramot at Tel Aviv University has signed a collaboration agreement with Bayer to develop and validate a platform for in vitro cardiotoxicity screening, using human heart tissues 3D-printed in Prof. Tal Dvir's Laboratory for Tissue Engineering and Regenerative Medicine at Tel Aviv University.

1 Jul 2020

New approach spurs production of antibiotic or antiparasitic compounds in bacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

26 Jun 2020

Using organic electrochemical transistor to measure extracellular electron transfer in bacteria

Scientists at Laboratory of Organic Electronics, Linköping University, have developed an organic electrochemical transistor that they can use to measure and study in fine detail a phenomenon known as extracellular electron transfer in which bacteria release electrons.

18 Jun 2020

Human stem cell models reveal neurodegeneration in glaucoma

Glaucoma, a serious eye condition responsible for causing vision loss, affects over three million Americans.

12 Jun 2020

Study reveals structure of an activated dopamine receptor

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

‘Terminator’ protein halts tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

4 Jun 2020

Bacteria that live in soil and on people have widespread antibiotic-destroying genes

The latest generation of tetracyclines - a class of powerful, first-line antibiotics - was designed to thwart the two most common ways bacteria resist such drugs.

3 Jun 2020

UCL scientists discover genes responsible for maintaining healthy hearing

Scientists at UCL have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) in humans.

From University College London 3 Jun 2020

Research project launched to find new treatments for rare genetic diseases

The University Carlos III Madrid, Almirall, S.A. and the MEDINA Foundation have launched a project to find new treatments for recessive dystrophic epidermolysis bullosa and other genetic diseases caused by nonsense mutations.

29 May 2020

Pre-existing genes can promote metastasis

Cancer can sometimes remain dormant, but it usually metastasizes and spreads to new sites in the body.

27 May 2020

Enhancement Of Bitter Taste Sensor Reduces Salt Intake

High salt intake is a well-known risk factor for hypertension and cardiovascular diseases. Reducing salt intake can lower blood pressure.

19 May 2020

The Global Hunt To Block COVID-19

A molecular biologist is working with a world leader in artificial intelligence-based drug discovery to help find a molecule that could prevent SARS-CoV-2.

19 May 2020