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80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health.

5 Oct 2020

Microscope Lens Inspired By Lighthouse

An optical device that resembles a lighthouse lens can make it easier to peer into Petri dishes and observe molecular-level details of biological processes.

5 Oct 2020

Scientists identify new ingredient that makes vaccine more effective

A number of vaccines contain ingredients known as adjuvants that make them more effective by triggering a more powerful immune response.

5 Oct 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

Study offers explanation to why people respond differently to the same drug

Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.

5 Oct 2020

Study unravels how immunotherapy is 'uniquely suppressed' by liver cancers

Though cancer immunotherapy has become a promising standard-of-care treatment--and in some cases, perhaps a cure--for a wide variety of different cancers, it doesn't work for everyone, and researchers have increasingly turned their attention to understanding why.

5 Oct 2020

Understanding beta-cell growth mechanisms may help treat metabolic diseases

New treatments for metabolic diseases, such as type 2 diabetes, could emerge from a study of how a single enzyme controls the growth of the pancreatic cells that produce insulin.

5 Oct 2020

Type and direction of force on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

5 Oct 2020

Gut microbial development could be restored in C-section infants by fecal microbiota transplant

The human gut contains a diverse ecosystem of microbes: mainly bacteria, as well as viruses and fungi, termed the gut microbiota.

5 Oct 2020

Researchers map genetic networks controlling human regulatory T cell identity

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

5 Oct 2020

Researchers develop a new technique to improve treatment for pancreatic cancer

Scientists have described the individual cells comprising the pancreatic cancer microenvironment.

5 Oct 2020

Scientists discover new genes and brain circuits crucial for short-term memory

A mice study has revealed a novel gene that is crucial for short-term memory but works in a part of the brain that is not usually linked to memory.

5 Oct 2020

Researchers identify small molecules that target a structure within SARS-CoV-2 genome

SARS-CoV-2 is a virus that is responsible for causing COVID-19. This pathogen has now crippled economies, health care systems, and everyday lives across the world.

5 Oct 2020

Study warns the negative effects of ocean warming and acidification on planktonic communities

A new study led by researchers from the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona warns that the negative effects of rapid ocean warming on planktonic communities will be exacerbated by ocean acidification.

1 Oct 2020

Researchers uncover problems with the conventional method for growing organoids

Organoids are stem cell-based tissue surrogates that can mimic the structure and function of organs, and they have become a key component of numerous types of medical research in recent years.

1 Oct 2020

Researchers identify key molecules that contribute to radioresistance in glioblastoma

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

1 Oct 2020

Researchers identify new mechanism that protects against Salmonella infection

Mice study has revealed a formerly unknown interaction between an immune cell protein and molecules extracted from dietary fiber.

30 Sep 2020

Researchers use multiple techniques to understand the effect of aging in humans

Humans’ hair becomes grey, their strength diminishes, and a host of age-related diseases represent what is occurring both at the molecular and cellular levels.

30 Sep 2020

Study offers clues to optimize defense tactics against viruses

Science's pursuits of unraveling how human cells fight viral infections kicked into high gear in 2020 with the devastating emergence of the SARS-CoV-2 virus.

30 Sep 2020

Genetic factor enables regeneration of adult skin like a newborn's

A newly identified genetic factor allows adult skin to repair itself like the skin of a newborn babe. The discovery by Washington State University researchers has implications for better skin wound treatment as well as preventing some of the aging process in skin.

30 Sep 2020