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Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

From Harvard Medical School 20 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

Study shows how herpesvirus invades human cells and causes chickenpox

Inspite of several years of research, scientists are still clueless about how herpesviruses penetrate the human cells.

20 Aug 2020

Study shows age is a major risk factor for dying from COVID-19 infection

According to a study, genes that play a significant role in enabling SARS-CoV-2 to penetrate the heart cells become more active as people age.

20 Aug 2020

Gene targeting could lead to better treatment of glioblastoma tumors

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma.

19 Aug 2020

Shielded stem cells can improve heart healing

Ghanta, R.K., et al. (2020) Immune-modulatory alginate protects mesenchymal stem cells for sustained delivery of reparative factors to ischemic myocardium. Biomaterials Science. doi.org/10.1039/D0BM00855A.

19 Aug 2020

Novel molecular survival strategy of Shigella bacterium uncovered

Enteric pathogens, such as the bacterium Shigella, can cause severe intestinal disease with bloody diarrhea. In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered a novel molecular survival strategy by which Shigella is able to cause damage to the intestines despite two elaborate protective mechanisms used by host cells.

19 Aug 2020

Surface structure of SARS-CoV-2 virus offers insights for development of therapeutics

At the start of a COVID-19 infection, the coronavirus SARS-CoV-2 docks onto human cells using the spike-like proteins on its surface. The spike protein is at the centre of vaccine development because it triggers an immune response in humans.

19 Aug 2020

Researchers uncover a novel biochemical mechanism fundamental to plant life

University of Adelaide researchers as part of a multidisciplinary, international team, have uncovered a new biochemical mechanism fundamental to plant life.

19 Aug 2020

Researchers study how bacteria adapt to their host cells

In the environment, they are often found inside unicellular organisms. A research team led by Matthias Horn at the Centre for Microbiology and Environmental Systems Science at the University of Vienna has made use of laboratory experiments to gain a better understanding of how these bacteria adapt to their host cell over time.

19 Aug 2020

LJI scientists tracked down rare stem cells that generate neutrophils in humans

Neutrophils are the warriors of the immune system. They are always ready to spring to action to help heal injuries or fight off disease. Unless, that is, something goes wrong in their developmental process.

19 Aug 2020

Study investigates how Ebola virus adapts to bat and human cells

A new study by researchers from The University of Texas Medical Branch at Galveston uncovered new information on why the Ebola virus can live within bats without causing them harm, while the same virus wreaks deadly havoc to people.

19 Aug 2020

Researchers discover the exit route for Vibrio bacteria from cells

As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape. After all, once it is in and multiplies, the bacterium must find a way out to infect new cells.

19 Aug 2020

Scientists propose a promising new tool based on optogenetics to study neurons

In many human endeavors, having good tools for a particular task is an essential requirement to obtain the best results possible, and neuroscience is no different than other scientific fields in this regard.

19 Aug 2020

Drugs designed to lower alpha-ketoglutarate levels could help fight DIPG tumors

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures.

19 Aug 2020

RNA-based therapeutic approach could be used to cure hereditary diseases

Short RNA molecules can be used as medication. Their effectiveness is based on the genetic information they carry: therapeutic RNA can bind to the body's own RNA and thus influence how it functions.

19 Aug 2020

Novel gene editing approach removes latent herpes simplex virus 1

Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.

19 Aug 2020

Study shows DNA damage causes cells to reprogram themselves into stem cells

Researchers have discovered that when DNA in the moss Physcomitrella patens is damaged, it causes cells to reprogram on their own to change into stem cells.

19 Aug 2020