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Revolutionizing Drug Design with Light-Activated Molecular Machines

Cells “talk” to one another to coordinate crucial biological activities such as immune activation, muscle contraction, hormone release, neuronal firing, and digestion using calcium signaling as a primary mechanism.

11 Jul 2023

Investigating the Seasonal Dynamics of the Wastewater Microbiome

The composition of the bacterial community in wastewater is influenced by the community of microbial predators. This describes seasonal variations in the microbial community that impact water treatment efficacy.

11 Jul 2023

C. auris in Ear Canals of Stray Dogs Could Pose Risk to Humans

Researchers from McMaster University and the University of Delhi in India have isolated and identified the first live culture of the drug-resistant pathogen Candida auris from an animal, particularly from the ear canals of stray dogs.

10 Jul 2023

Fragile Symbiosis Between Fungus and Bacteria Revealed

A new study on the coexistence of bacteria and fungi shows that a mutually beneficial, functioning symbiosis can be very fragile.

7 Jul 2023

Gut Microbes Could Be Harnessed to Block Mercury Absorption

New research by a team at Pennsylvania State University suggests that microbes in the human gut could be harnessed to block absorption of toxic metals like mercury and help the body absorb useful nutritional ones, like iron.

5 Jul 2023

Host Genetics Affects Composition of Switchgrass Root Microbiome

Plants provide a home for a wide diversity of microbes, especially in their roots. In turn, these communities can provide important benefits for the host.

5 Jul 2023

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Feng Zhang of the Broad Institute at MIT and Harvard and the McGovern Institute for Brain Research at MIT headed a team of researchers who discovered the first programmable RNA-guided mechanism in eukaryotes, which include fungi, plants, and animals.

29 Jun 2023

The Influence of Streptomyces on Soil Microorganisms

Chemical substances called arginoketides, which are produced by bacteria of the genus Streptomyces, cause a variety of reactions in other microorganisms: Algae group together to form aggregates, fungi produce signaling molecules that they would not otherwise produce, and bacteria develop biofilms that cause other organisms to respond differently.

28 Jun 2023

Probiotic Bacteria may Help Maintain Brain Function in Aging Nematodes

A group from Nagoya University in Japan has discovered that when the diet of nematodes, tiny worms measuring about a millimeter or less in length, includes the bacteria Lactobacillus reuteri, the weakening of associative learning ability caused by aging does not occur.

28 Jun 2023

Novel Drug Slows Development of Antibiotic Resistance

At the Baylor College of Medicine, a research group is gaining ground in its quest for solutions to the global concern of bacterial antibiotic resistance, which was accountable for almost 1.3 million deaths in 2019.

26 Jun 2023

New Oral Probiotic Delivery System Keeps “Good” Bacteria Safe

Probiotics can help maintain a healthy gut microbiome or rebuild populations of “good bacteria” following an antibiotic course. They may now be utilized as a viable treatment strategy for certain intestinal diseases like Crohn’s disease.

22 Jun 2023

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

The amount of data generated by scientists today is massive, thanks to the falling costs of sequencing technology and the increasing amount of available computing power.

22 Jun 2023

Using Enzyme Inhibitors to Assess the Potential for Antimicrobial Resistance

Early tests revealed that MK-3402, an experimental metallo-beta-lactamase inhibitor, was well tolerated after administration to healthy individuals.

19 Jun 2023

VOLT to Focus on VOC Gases in Plankton, Soil, and Moss

It is vital to determine how much gas is released into the atmosphere by plants, soil, fungi, and bacteria. The gases they emit have an impact on the planet’s climate, yet very little is known about them.

19 Jun 2023

Small RNA Identified as Regulator During Bacterial Infection

Infection risk is always there in those with compromised immune systems. Pseudomonas aeruginosa, a typical environmental bacterium, can colonize several body areas, including the lungs.

15 Jun 2023

New Data Shows Gene Expression at Different Stages of Pregnancy

While the exterior features of a woman can alter throughout pregnancy, scientists are surprisingly ignorant about the interior biological changes that take place.

14 Jun 2023

cBAF Protein Complex Controls the Fate of T Cells

The immune system protects the body from intruders, like bacteria, viruses, or tumors, with its intricate network of proteins, cells, and organs. Cytotoxic T cells are specialized immune cells that can grow into short-lived effector cells that destroy infected or malignant cells in human bodies.

14 Jun 2023

Reengineering the Cellular Synthetic Machinery to Produce Never-Before-Seen Polymers

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals -; from fuels to fabrics and drugs -; beyond the normal repertoire of microbes.

14 Jun 2023

UCL Scientists Visualize the Molecular 'Nano-Machinery' That Causes Cilia to Beat

The first image of the structures that power human cilia – the tiny, hairlike projections that line our airways – has been produced by a team involving UCL researchers and could lead to much-needed treatments for people with rare cilial diseases.

14 Jun 2023

Researchers Discover Novel Combination Therapy to Counter Antibiotic-resistant Mycobacterium Abscessus Infections

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Nanyang Technological University Singapore (NTU Singapore) and National University Hospital (NUH), have discovered a novel therapy by combining two antibiotics, rifaximin and clarithromycin, to treat Mycobacterium abscessus (M. abscessus), a non-tuberculous mycobacterium (NTM) that causes chronic lung-related infections.

9 Jun 2023