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Gene-Edited Bacteria Increases Nitrogen Fixation in Corn

If corn ever felt envious of soybean’s relationship with nitrogen-fixing bacteria, advancements in gene editing may one day level the playing field.

17 Jan 2025

AI-Powered Platform for Designing Novel Protein Interactions

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for biomedicine by using deep learning to create new proteins that bind to complexes involving other small molecules, such as hormones or medications.

17 Jan 2025

New study reveals how genes switch on and off in human cells

An international group of scientists has made a significant advancement in their understanding of the regulation of gene expression throughout the human genome.

17 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Researchers Develop Strategy to Boost Pharmaceutical Production in CHO Cells

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

16 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Study Reveals Key Ion Channel in Extracellular Vesicles for Cargo Transport

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their membranes intact as they negotiate shifting electrical impulses in different biological environments.

16 Jan 2025

Epigenetic Mechanism Controls Placental Blood Vessel Formation

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of Heidelberg University discovered that the correct development of functioning blood vessels in the mouse placenta is controlled epigenetically: One of the enzymes that modify gene activity using methyl groups is responsible.

16 Jan 2025

Long Reads Show Promise for Diagnosing Rare Genetic Disorders

The cause of rare diseases is increasingly being detected through genome sequencing, which involves reading the entire human DNA by first breaking it into small pieces-short reads.

16 Jan 2025

Breakthrough in Understanding Semliki Forest Virus Neuro-Invasion

In a recent study, researchers from Uppsala University show that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain.

16 Jan 2025

Protein Shapes Reveal Deeper Evolutionary Relationships

According to a study published in the journal Nature Communications, the three-dimensional form of a protein can be utilized to determine long-standing evolutionary relationships in the tree of life.

16 Jan 2025

Human H5N1 Bird Flu More Virulent in Mice Than Bovine Strain

Researchers from the Texas Biomedical Research Institute reported in the journal Emerging Microbes & Infections that one of the first strains of bird flu to be isolated from a human in Texas exhibits a distinct set of mutations that allow it to more readily replicate in human cells and inflict more severe disease in mice than a strain found in dairy cattle.

16 Jan 2025

Is Calcium Signaling the Bridge Between Unicellular and Multicellular Life?

Calcium-dependent signaling in S. rosetta uncovers mechanisms of cellular coordination, shedding light on the evolution of multicellularity and sensory systems.

16 Jan 2025

Study Identifies Five Root-Lesion Nematodes Affecting New Zealand Maize

A new study has lifted the lid on five species of root-lesion nematodes living in maize crops across New Zealand - and suggested the existence of a hitherto-unsuspected cryptic species.

15 Jan 2025

Friendly Germs May Hold the Key to Overcoming Antimicrobial Resistance

Friendly germs armed with their own biological syringes and poisons could hold the key to overcoming the antimicrobial resistance crisis, according to a new study by biologists at the Universities of Manchester and Basel.

15 Jan 2025

Terumo BCT and FUJIFILM Irvine Scientific Partner to Optimize T Cell Expansion Process

Terumo Blood and Cell Technologies (Terumo BCT), and FUJIFILM Irvine Scientific have announced a strategic collaboration to help accelerate T cell expansion using Fujifilm's PRIME-XV® T Cell Expansion Media on Terumo BCT’s Quantum Flex™ Cell Expansion System. By using systems that work together, this collaboration offers an optimized workflow solution with a ready-to-use process, aimed at reducing the barriers in scaling T cell expansion.

15 Jan 2025

Compound from Sea Sponge Could be Used as a Chemical Probe for Research

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects.

15 Jan 2025

Unrepaired DNA Damage Can Persist for Years and Lead to Cancer Mutations

While most known types of DNA damage are fixed by our cells’ in-house repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer.

15 Jan 2025