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Harnessing Proteomics to Explore the Role of Probiotic Bacteria in Human Health

The currently available proteomics strategies can be used to identify and quantify probiotic bacterial proteins.

19 Aug 2024

Advancing Cardiovascular Drug Discovery: Translational Framework Leverages Genetic and Proteomic Insights

A validated framework to translate these recent advances in genoproteomics into clinical applications in cardiovascular drug development.

19 Aug 2024

Insights into Host Defense Mechanisms Through Cell Death and Immune Pathways

A new review was published as the cover paper of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 15, entitled, "Types of cell death and their relations to host immunological pathways".

19 Aug 2024

New Tool Revolutionizes Cell Migration Research with Simplified Data Analysis

Studying cell migration is vital because it plays a crucial role in many biological processes, including immune response, wound healing, and cancer metastasis.

19 Aug 2024

Genetic Mapping of Lyme Disease Bacteria Offers New Diagnostic and Treatment Possibilities

A genetic analysis of Lyme disease bacteria may pave the way for improved diagnosis, treatment and prevention of the tick-borne ailment.

19 Aug 2024

Electrical Recordings Illuminate Neural Basis of Inferential Reasoning

It takes brains to infer how any two things in the world relate to each other, whether it's the way bad weather links to commuting delays or how environmental conditions lead to the evolution of species.

16 Aug 2024

New Insights into Cell Communication During Inflammation

Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation.

16 Aug 2024

New Insights into Cellular Regeneration Through Gap Closure Study

The National Institute of General Medical Sciences, a branch of the National Institutes of Health (NIH), has awarded Yubing Sun, associate professor of mechanical and industrial engineering at the University of Massachusetts Amherst, a $1.9 million Maximizing Investigators' Research Award to support the exploration of the fundamental principles behind the process that close gaps caused by injury or growth between cells.

16 Aug 2024

New Imaging Technique Offers Clearer View of Brain Function

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

16 Aug 2024

Global Effort Maps Genetic Makeup of Lyme Disease Bacteria

A team led by CUNY Graduate Center biologists has produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.

16 Aug 2024

Researchers Uncover Role of OpgH in Bacterial Cell Shape

In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's "envelope" or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.

16 Aug 2024

New Insights into Memory Formation and Modification

The ability to turn experiences into memories allows us to learn from the past and use what we learned as a model to respond appropriately to new situations. For this reason, as the world around us changes, this memory model cannot simply be a fixed archive of the good old days.

16 Aug 2024

Two Genes Control Explosive Taste Bud Growth in Cavefish

Over thousands of years, cavefish evolved and lost their vision, earning the moniker "the blind cavefish," but some cavefish also developed an inordinate number of taste buds on the head and chin.

16 Aug 2024

Spontaneous Brain Activity Drives Early Neural Circuit Formation

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog -; four legs, fur, a tail, etc. -; a young child will eventually be able to identify dogs going forward. But brain wiring begins before humans are born, before they have experiences or senses like sight to guide this cellular circuitry. How does that happen?

16 Aug 2024

Flavivirus Hijacks Importin-7 for Nuclear Transport and Replication

Viruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), Dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and Tick-borne encephalitis virus, are significant arthropod-borne pathogens.

15 Aug 2024

Study Uncovers Biomarkers for Low Muscle Mass, Offering Insights for Personalized Prevention

Machine learning models to analyze computed tomography (CT) images of the chest and a proteomics approach to determine blood protein biomarkers.

15 Aug 2024

New Approach for Targeted Genome Editing in Wild Populations

Researchers from Macquarie University and the California Institute of Technology have discovered a novel method that, when published in Nature Communications on August 13th, 2024, might make it easier and more controllable for scientists to modify the genetic composition of wild populations than when using gene drives.

14 Aug 2024

Astrocytes Emerge as Key Players in Brain Health and Development

Researchers at the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) and Duke-NUS Medical School have uncovered a novel mechanism for reawakening dormant neural stem cells, which may lead to the development of new treatments for neurodevelopmental disorders like autism, cerebral palsy, and learning disabilities.

14 Aug 2024

Mechanical Manipulation of Stem Cells Promises New Treatments

New stem cell therapies may result from a novel method that McGill researchers have created for mechanically modifying stem cells, which has not yet reached its full therapeutic potential.

14 Aug 2024

Lipid Accumulation Linked to Senescence in Dopaminergic Neurons

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid accumulation drives cellular senescence in dopaminergic neurons."

14 Aug 2024