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New technology to rapidly create antibody-drug conjugates

A USC School of Pharmacy-led team has engineered a new, faster way to make drugs that precisely target malignant cells - while leaving healthy tissue undamaged - that could lead the way to better treatments for numerous types of cancer.

5 Jun 2020

Single-cell-resolution technologies help map brain regions in humans and primates

Using the single-cell-resolution transcriptomics technologies, researchers have performed a large-scale analysis of gene expression in 33 different brain regions of chimpanzees, bonobos, macaques, and humans, and successfully generated a map of the various brain regions with their particular cell structures.

5 Jun 2020

New model decodes relationship between metabolic mechanisms and genes

New research introduces a unique mathematical method to study human metabolism by decreasing the complexities of the human genome-scale GEMs.

5 Jun 2020

Researchers identify bacterium responsible for causing intestinal bleeding in pigs

A research team from University of Bern has recently identified the reason behind a fatal intestinal bleeding in piglets caused by bacterium.

5 Jun 2020

C19ORF57 gene could advance reproductive medicine

The gene C19ORF57 has been identified to play a major role in meiosis by the Institute of Molecular Embryology and Genetics at Kumamoto University.

5 Jun 2020

New image of LSD1 enzyme in action could provide insight into gene regulation

New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells--including cancer cells--regulate their genes.

5 Jun 2020

Researchers discover how a microRNA protects vascular integrity

Ludwig-Maximilian-Universitaet in Munich researchers have discovered a hitherto unknown molecular function of a specific microRNA that preserves integrity of the endothelium and reduces the risk of atherosclerosis.

5 Jun 2020

Exploring the cradle of hematopoietic stem cells

Researchers from the group of Catherine Robin at the Hubrecht Institute characterized the molecular landscape of the aorta that supports the generation of the first Hematopoietic Stem Cells (HSCs) in the embryo.

5 Jun 2020

Scientists aim to develop a gene-targeting, antiviral agent to combat COVID-19

A team of scientists from Stanford University is working with researchers at the Molecular Foundry, a nanoscience user facility located at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), to develop a gene-targeting, antiviral agent against COVID-19.

5 Jun 2020

Salk researchers discover how cells remember their identity

Cancer is often the result of DNA mutations or problems with how cells divide, which can lead to cells "forgetting" what type of cell they are or how to function properly.

5 Jun 2020

New technique restores hearing in mice with a recessive genetic mutation

Using a new genetic engineering technique, known as base editing, researchers from Boston Children's Hospital and the Broad Institute of MIT and Harvard, have restored hearing in mice with a known recessive genetic mutation.

5 Jun 2020

Lab-grown organoids can prevent hair loss

Researchers have created a new, hair-germinating piece of human skin in the laboratory that might prevent hair loss in the days to come.

4 Jun 2020

Cryo-electron microscopy helps visualize PANX1 protein at near-atomic level

For the first time, researchers from Van Andel Institute have explained the near-atomic level structure of a molecular route that has crucial roles to play in the regulation of blood pressure, cell death, inflammation, and human development.

4 Jun 2020

Advanced microscopy techniques help visualize telomerase in living cells

Canadian researchers have made a major breakthrough in the analysis of telomerase, a crucial enzyme involved in cancer and aging.

4 Jun 2020

Study reveals how respiratory syncytial virus breaks into cells to cause infection

New research from University of Alberta microbiologists has shed new light on how the respiratory syncytial virus (RSV)--one of the most common viral infections--breaks into our cells to cause infection.

4 Jun 2020

‘Terminator’ protein halts tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

4 Jun 2020

Study uncovers why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

4 Jun 2020

Researchers identify key gene essential for leukemia stem cells' survival

Acute myeloid leukemia (AML) is one of the most common forms of blood cancer among adults and is associated with a low survival rate, and leads to the inhibition of normal blood formation.

4 Jun 2020

Research team discovers proteins that regulate interorganelle communication

Korea Brain Research Institute (KBRI headed by Suh Pann-ghill) announced on the 2nd that the joint research team of KBRI (team led by Dr. Mun Ji-young), Seoul National University, and Pohang University of Science and Technology discovered the proteins that engage in the formation of MAM, which is the cellular signaling hub.

4 Jun 2020

ETH researchers uncover a complex plant-bacteria interaction

Plants need nitrogen in the form of ammonium if they are to grow. In the case of a great many cultivated plants, farmers are obliged to spread this ammonium on their fields as fertilizer.

4 Jun 2020