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Mice study shows how air pollution reduces sperm count by causing brain inflammation

Researchers have long known that air pollution can increase the risk of disorders such as obesity, diabetes, and fertility, but they did not know the exact mechanism for how it can lead to these health conditions.

26 Oct 2021

Specific amino acids act against neurodegenerative processes, says study

Dementia is a condition that involves severe loss of cognitive function.

26 Oct 2021

'Switching on' Sight using Gene Therapy

AZoLifeSciences speaks to Dr. Raymond Wong about his latest research into eye health and we could potentially 'switch on' sight using gene therapy.

20 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Researchers discover how neurons filter distracting signals to coordinate movements

As you read this article, touch receptors in your skin are sensing your environment. Your clothes and jewelry, the chair you're sitting on, the computer keyboard or mobile device you're using, even your fingers as they brush one another unintentionally-;each touch activates collections of nerve cells.

15 Oct 2021

Researchers use photosynthetic microbes as an oxygen source for nerve cells

Each second, the nerve cells in the brain process numerous signals. And the energy needed to carry out these tasks is mostly generated by aerobic metabolism—the reason why the brain needs a constant supply of oxygen.

15 Oct 2021

Research reveals involvement of secretory granules in Parkinson’s disease

Recent research states that the number of secretory granules (SGs) in tyrosine hydroxylase-positive neurons and the marker proteins secretogranin III substantially lowered in the substantia nigra and striatum regions of mice exposed to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine.

13 Oct 2021

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

12 Oct 2021

Neuronal variability boosts learning and performance, says research

Scientists from Imperial College London discovered that variation between brain cells might accelerate learning and enhance the functioning of the brain and future AI.

8 Oct 2021

Study uncovers a protein that indicates whether emotional memories can be changed

Researchers have discovered that a particular protein can be used as a brain marker to indicate whether emotional memories can be changed or forgotten.

5 Oct 2021

Ketone supplement may be a new therapeutic strategy for enhancing brain health in adults with obesity

New research published in The Journal of Physiology has shown that ketone supplements may be a novel therapeutic strategy for protecting and improving brain health in people with obesity.

5 Oct 2021

Gene therapy turns glial brain cells into neurons, restores visual function

A team of scientists identified a means to employ gene therapy to convert glial brain cells into neurons, reinstating visual function.

4 Oct 2021

Study offers important insights into how circadian clocks function at the subcellular level

Almost every living thing on Earth-;from bacteria to plants to people-;have a circadian rhythm, the biological clock that controls both physiology and behavior of organisms over a 24-hour period.

1 Oct 2021

Experts state muscle-secreted neurturin provides similar results as exercise

Scientists from the Karolinska Institutet pinpointed a protein that enhances motor coordination, muscular metabolism, and exercise performance in mice.

1 Oct 2021

Gene expression changes help understand the mechanism behind noise-induced hearing loss

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

30 Sep 2021

Stringent lineage tracing crucial for studies of nerve cell regeneration

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

30 Sep 2021

Exploring cell and gene based therapies for Parkinson’s disease

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

24 Sep 2021

Discovery may offer a promising new path for the study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Microglial cells join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Researchers reverse Kleefstra syndrome after birth in a mouse model

Scientists announced the reversal of Kleefstra syndrome—a genetic disorder leading to intellectual disability.

23 Sep 2021

Neurons News and Research

Mice study shows how air pollution reduces sperm count by causing brain inflammation

Specific amino acids act against neurodegenerative processes, says study

'Switching on' Sight using Gene Therapy

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Researchers discover how neurons filter distracting signals to coordinate movements

Researchers use photosynthetic microbes as an oxygen source for nerve cells

Research reveals involvement of secretory granules in Parkinson’s disease

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

Neuronal variability boosts learning and performance, says research

Study uncovers a protein that indicates whether emotional memories can be changed

Ketone supplement may be a new therapeutic strategy for enhancing brain health in adults with obesity

Gene therapy turns glial brain cells into neurons, restores visual function

Study offers important insights into how circadian clocks function at the subcellular level

Experts state muscle-secreted neurturin provides similar results as exercise

Gene expression changes help understand the mechanism behind noise-induced hearing loss

Stringent lineage tracing crucial for studies of nerve cell regeneration

Exploring cell and gene based therapies for Parkinson’s disease

Discovery may offer a promising new path for the study of multiple sclerosis

Microglial cells join together to break down toxic proteins more quickly

Researchers reverse Kleefstra syndrome after birth in a mouse model

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