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Researchers design a molecule that prevents the replication of coronaviruses

Researchers have created a molecule that suppresses coronavirus replication and has the potential to be developed into a COVID-19 treatment drug.

14 Feb 2022

Genetic mutation introduced into human genome protects against Alzheimer’s disease, research says

Scientists were successful in editing the genome of human cells cultured in vitro to introduce a mutation offering protection from Alzheimer’s disease.

14 Feb 2022

Three proteins as potential new therapeutic targets in movement disorders

Three members of a family of proteins have been identified that are important to helping us fine tune the activity of brain chemicals which enable us to walk or stand at will, scientists report.

11 Feb 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Scientists design an open microfluidic system for excellent recovery of purified DNA

In the war against cancer, the first step towards treating them is an accurate diagnosis of the problem. A technique that helps plan a better course of treatment is a biopsy.

7 Feb 2022

Study provides insight into the mechanism of action of DNA topoisomerase VI at the molecular level

The enzyme DNA topoisomerase VI (topo VI) plays a vital role in eliminating chromosome tangles that arise in the cell nucleus of plants.

4 Feb 2022

Researchers discover a sustainable approach for drug development

Although several people think of medicines as purely synthetic compounds, nature is an important element of most of the medications humans depend on.

4 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Ingenza collaborates with Johnson Matthey for efficient industrial enzyme synthesis

Biotechnology company Ingenza is excited to report the successful conclusion to its recent six-month project with Johnson Matthey.

1 Feb 2022

Producing New Antibiotics Through Gene Editing

In this interview, we speak to Professor Jason Micklefield about his latest research that may be able to produce new antibiotics through gene-editing technologies.

From The University of Manchester 24 Jan 2022

Researchers analyze motor protein movement in neurons

A thread-like highway, called microtubule tracks, allows motor proteins to transport cargo inside neurons.

21 Jan 2022

Researchers discover new imperfection in the way Rubisco functions in cowpea

A single enzyme is responsible for assimilating carbon dioxide in photosynthesis to create all the carbon in human bodies, in food, and in the biosphere as a whole.

21 Jan 2022

Researchers identify new potential drug target that may block SARS-CoV-2 infection

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host's cells.

17 Jan 2022

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

WEHI researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 13 Jan 2022

Scientists examine key mechanisms underlying genomic imprinting

Hereditary diseases, along with cancers and cardiovascular diseases, may be linked to genomic imprinting.

13 Jan 2022

Scientists develop DNA-based fluorescent nanoantenna to evaluate protein activity

Researchers at the Université de Montréal have developed a nanoantenna to track protein movements.

13 Jan 2022

Scientists discover new Senp5S protein with crucial role in brain development

Understanding how the brain develops is crucial to formulating treatments and management protocols for a variety of developmental disorders, as well as degenerative neurological diseases. Right from the embryonic stage, brain development is facilitated by the differentiation of neurons (brain cells).

12 Jan 2022

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Doctors monitor kidney transplant recipients for signs of rejection in several ways, including biopsy.

7 Jan 2022

Researchers develop new CAR T cells that act as a "micropharmacy"

Immunotherapies called chimeric antigen receptor (CAR) T cells use genetically engineered versions of a patient's own immune cells to fight cancer. These treatments have energized cancer care, especially for people with certain types of blood cancers.

3 Jan 2022