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Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

Allergic immune responses protect against bacterial infections

Allergy is one of the most common diseases in Europe, it is estimated that more than 150 million Europeans suffer from recurring allergies and by 2025 this could have increased to half of the entire European population.

10 Sep 2020

Human evolution shaped by pathogens and cell-autonomous immunity

Every human cell harbors its own defenses against microbial invaders, relying on strategies that date back to some of the earliest events in the history of life, researchers report.

10 Sep 2020

Research shows how mutations in DNA packaging machines can drive cancer development

Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.

9 Sep 2020

Researchers establish new consortium to study the effect of mutations on the blood characteristics

A team of researchers has established an international consortium to analyze the blood of scores of people across the globe.

7 Sep 2020

Researchers determine how prokaryotic and single-celled origins contribute to human evolution

Immune responses are produced by a complex, hierarchical organization of the immune system, tissues, organs, and components.

7 Sep 2020

Researchers discover the developmental process of strong immune T-cells

There are memory cells that remember previously encountered pathogens and help to react quickly and strongly when exposed to them again.

4 Sep 2020

Researchers discover the developmental process of novel immune T cells

Memory cells essentially recall formerly encountered pathogens and help respond strongly and rapidly when they are exposed to this foreign matter again.

3 Sep 2020

Active ingredients found in sunscreen have detrimental effects on freshwater ecosystems

The active ingredients found in sunscreen have detrimental effects on freshwater ecosystems, according to new research by University of Alberta biologists.

3 Sep 2020

Metastatic cancer cells reshape, destroy or integrate into blood vessels

In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.

2 Sep 2020

Understanding skin damage caused by rubbing could lead to better topical skin treatments

Understanding the skin damage caused by rubbing could lead to better topical skin treatments and help prevent the formation of new routes for viral and bacterial infection.

31 Aug 2020

New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

Rare disorder of fat metabolism can cause chronic hyperreaction of the immune system

A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system. This is the conclusion reached by researchers from the University of Bonn in a recent study.

25 Aug 2020

LJI scientists tracked down rare stem cells that generate neutrophils in humans

Neutrophils are the warriors of the immune system. They are always ready to spring to action to help heal injuries or fight off disease. Unless, that is, something goes wrong in their developmental process.

19 Aug 2020

Study sheds light on genetic and molecular mechanisms involved in atopic dermatitis

The KIF3A gene contains common variants that raise the risk of a dysfunctional skin barrier and ultimately lead to a skin condition, called atopic dermatitis.

17 Aug 2020

NIH-supported research delineates how genetic variations cause atopic dermatitis

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.

17 Aug 2020

Exercise induces changes in sweat biomolecule levels, shows study

A new study shows that in addition to blood, endurance exercise induces changes in sweat biomolecule levels. These findings lay the groundwork for the development of future noninvasive exercise monitoring systems that utilize sweat as a biomarker source.

13 Aug 2020

Researchers are testing new way to deliver vaccines through microneedle skin patches

A revolutionary new way to give vaccines through microneedle skin patches is being tested at Swansea University, thanks to £200,000 of EU funding announced by the Welsh Government.

10 Aug 2020

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

How tumor cells evade the immune defense

A new study by the University of Bonn and research institutions in Australia and Switzerland now shows the strategies tumor cells use to evade this attack.