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Astrocytes Emerge as Key Players in Brain Health and Development

Researchers at the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) and Duke-NUS Medical School have uncovered a novel mechanism for reawakening dormant neural stem cells, which may lead to the development of new treatments for neurodevelopmental disorders like autism, cerebral palsy, and learning disabilities.

14 Aug 2024

Utah Scientists Begin New Project to Map Epigenetic Changes Across the Human Genome

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved.

12 Aug 2024

Study Explores the Role of Sex-Biased Gene Expression in Autism Risk During Prenatal Development

The cortex of prenatal donors to determine differentially expressed genes based on sex and potentially identify molecular and cellular mechanisms that contribute to ASD.

7 Aug 2024

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

2 Aug 2024

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years.

1 Aug 2024

Cost-Effective Array Sheds Light on Imprinted Gene Regulation

Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array represents a cost-effective, efficient method for exploring potential links between environmental exposures and epigenetic dysregulation during the early developmental origins of diseases and behavioral disorders.

26 Jul 2024

Researchers Discover Genes Key to Spitting Cobra Venom's Cytotoxicity

Functional genomics to dissect and understand the cytotoxicity of spitting cobra venom and define the genetic interactions between the venom and the target to develop a locally acting antidote.

25 Jul 2024

Study Shows the Impact of Exposome on Serum Metabolites in Children

The combined effect of environmental exposures and unhealthy lifestyle habits can affect children's cardiometabolic health in a way that exceeds their separate effects.

24 Jul 2024

The Protein STAT3 Helps the Immune System Fight Leukemia

Study at the Karl Landsteiner University of Health Sciences uncovers unknown interaction between leukemic cells and immune cells. Potential biomarkers for future immunotherapies found.

From Karl Landsteiner University of Health Sciences 17 Jul 2024

Harnessing Enzymes for Making RNA Therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

15 Jul 2024

Macrophage Inflammation may Contribute to LSD Symptoms

Researchers at The Hospital for Sick Children (SickKids) have found that inflammation in an immune cell may be responsible in part for some severe symptoms in a group of rare genetic conditions called lysosomal storage diseases (LSDs).

15 Jul 2024

Using Mobile Data to Track the Spread and Evolution of Superbugs

Key insights into the global spread, evolution, and resistance patterns of a major bacterium causing pneumonia and meningitis have been revealed through the combination of genomic data and human travel patterns over 14 years in South Africa.

4 Jul 2024

TRPC5 Gene Alterations: A Key Player in Obesity and Postpartum Depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

3 Jul 2024

Study Offers Insights Genetic Variants Influencing Pubertal Timing

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

2 Jul 2024

Mice Studies Shed Light on Serotonin and Memory

Memory regulation in humans and animal models is regulated by the serotonin 2C receptor in the brain, according to research from Baylor College of Medicine, the University of Cambridge in the United Kingdom, and affiliated institutions.

1 Jul 2024

Primitive Endoderm Stem Cells Offer New Hope for Fertility Treatments

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen.

25 Jun 2024

St. Jude Researchers Discover NLRC5's Role in Inflammatory Cell Death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

17 Jun 2024

New Clinical Trial Offers Path to Sickle Cell Cure

The most recent results from a clinical trial were given by researchers in an effort to find a cure for sickle cell disease, a painful genetic blood illness that has few available treatments.

17 Jun 2024

New Method Offers Rapid and Accurate Blood Infection Detection

Researchers have shown that a novel method could identify bloodstream infections precisely and swiftly. The study findings were presented at ASM Microbe, the annual meeting of the American Society for Microbiology.

17 Jun 2024

Exploring the Use of Weakened Viruses for Cancer Treatment

Scientists at Northwestern Medicine have found that an attenuated virus can aid in the elimination of cancer in mice. Furthermore, mice given this virus treatment had a higher lifetime tumor-prevention rate.

12 Jun 2024