Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Study: Platelets likely to perform a protective function in AD

A new research paper was published on the cover of Aging entitled, "Immune-mediated platelet depletion augments Alzheimer's disease neuropathological hallmarks in APP-PS1 mice."

16 Feb 2023

Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

Here is an important reason to stay in touch with friends and family: social isolation causes memory and learning deficits and other behavioral changes.

15 Feb 2023

New ways to diagnose learning and memory disorders

By showing Welles's movie "Touch of Evil" to mice, Chinmay Purandare, PhD, and Prof. Mayank Mehta of UCLA have uncovered surprising and important new insights about how neurons form memories. The discovery points to new ways to diagnose Alzheimer's and other learning and memory impairments, while also improving artificial intelligence.

15 Feb 2023

Characterizing the transcription profile of microglia in a mouse model

Researchers from Tohoku University have now shown that the consolidation and extinction of contextual fear conditioning alter the microglial genes connected to the synapse—structures that permit neurons to communicate with one another.

13 Sep 2022

The deep relationship between Tob gene and common mental health conditions

The Tob gene is well known for its connection to cancer. Scientists have discovered that this gene also has a significant role in lowering depression, fear, and anxiety in a multidisciplinary study that blends molecular biology with neuroscience.

12 Sep 2022

Brain cells with the same birthdate display distinct connectivity

According to a recent study, brain cells with the same “birthdate” are more likely to connect into cooperative signaling circuits that perform a variety of tasks, including memory storage.

From New York University (NYU) 25 Aug 2022

Researchers discover key cells that control interaction in parts of the brain

A research group from MedUni Vienna’s Center for Brain Research has identified key cells that control data communication between parts of the brain.

18 Jul 2022

Study identifies the crucial activity of transposable elements in the evolution of the octopus genomes

The octopus is an extraordinary organism with exceptional brain complexity and cognitive abilities that are unmatched by other invertebrates. So much so that it resembles vertebrates in certain ways more than it does invertebrates.

1 Jul 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Newborn cells in patients with epilepsy, likely to provide a potential treatment

According to a study headed by researchers from USC Stem Cell and the USC Neurorestoration Center, adults may recover at least some of what they have lost by producing new brain cells, and this process is profoundly modified in patients with long-term epilepsy.

7 Apr 2022

Researchers discover 15 genetic 'hotspots' that speed up or slow down brain aging

Researchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow it down -; a finding that could provide new drug targets to resist Alzheimer's disease and other degenerative brain disorders, as well as developmental delays.

6 Apr 2022

Study finds surprisingly few connections between far-reaching regions of the brain

Understanding how the brain functions, particularly how information is processed during different activities, is difficult without knowing how many axons are in the brain and how many connect different functional regions.

25 Mar 2022

Astrocyte networks are essential for spatial learning and memory formation, study shows

Astrocytes form large networks of interconnected cells in the central nervous system. When these cell-to-cell couplings are disrupted in the brain of adult mice, the animals are no longer able to store spatial information.

9 Mar 2022

Respiration entrains and coordinates neuronal activity in various brain regions

LMU neuroscientists have shown that breathing coordinates neuronal activity throughout the brain during sleep and quiet.

25 Jan 2022

Mysterious protein clusters found on neurons are calcium-signaling “hotspots”, study reveals

For 30 years, mysterious clusters of proteins found on the cell body of neurons in the hippocampus, a part of the brain, both intrigued and baffled James Trimmer.

From The University of California, Davis 15 Nov 2021

New insights into the role of fat cells in cognitive decline and neurodegeneration

Findings published this week reveal new insights into the role of fat cells in cognitive decline and neurodegeneration, according to a study that involves the oxidant amplification loop led by Marshall University scientists.

22 Oct 2021

Researchers discover that existing drug can enhance memory

A group of scientists identified that a prevailing drug for treating constipation might boost an individual’s capability to think with better clarity.

4 Oct 2021

UMSOM study suggests a genetic basis behind instantaneous human compatibility

Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why?

2 Sep 2021

Study reveals how 3D space is represented in the mammalian cortex by the brain's 'GPS'

In a new study published in Nature today, Weizmann Institute of Science researchers, in collaboration with colleagues from the Hebrew University of Jerusalem, unveiled for the first time how three-dimensional space is represented in the mammalian cortex by the brain's "GPS" system.

13 Aug 2021

Study discovers link between corticosteroid receptors and hippocampal neuroplasticity, ciliary genes

Chronic stress is a well-known cause for mental health disorders. New research has moved a step forward in understanding how glucocorticoid hormones ('stress hormones') act upon the brain and what their function is.

9 Aug 2021