Immunotherapy News and Research

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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

Localized Delivery Minimizes Side Effects of Immunotherapy

Cancer is the monster of the society.. The American Cancer Society reports that over 600,000 Americans lost their lives to cancer in the previous year. Medical progress has been shaped by the unwavering quest to understand this complex disease, leading to the development of less invasive yet highly effective treatment procedures.

22 Apr 2024

Cataloging Bacteria in Cancer Metastases

Researchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases.

10 Apr 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024

Exploring the Link Between Gut Health and Effective Milk Allergy Treatment

Exploring the Link Between Gut Health and Effective Milk Allergy Treatment At the RIKEN Center for Integrative Medical Sciences in Japan, researchers under the direction of Hiroshi Ohno have found a connection between gut microbiota and the effectiveness of oral immunotherapy for milk allergies.

15 Mar 2024

DNA Origami Revolutionizes Cancer Immunotherapy: The DoriVac Breakthrough

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Dual-Target CAR T Cell Therapy Shows Promise Against Recurrent Glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2024

First Whole Genome Sequencing of Male Breast Cancer Reveals Potential Treatment Targets

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

5 Mar 2024

Unlocking the Potential of Microbiome-Based Cancer Therapies

The microbiome can identify patients with rare gynecological cancers, biliary tract cancers, and melanoma who will benefit from combination immunotherapy for various cancer types.

4 Mar 2024

Novel Gene Signature Identified for Predicting Immunotherapy Response in NSCLC

A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation.

26 Feb 2024

Newly Found Memory B Cell Remembers Allergies

A new cell that remembers allergies has been discovered by researchers from McMaster University and the Danish pharmaceutical company ALK-Abello A/S.

8 Feb 2024

Pore Power: High-Speed Droplet Production In Microfluidic Devices

Over the last two decades, ongoing research in microfluidics has faced challenges in applications due to the restricted productivity of microdroplets.

7 Feb 2024

Imec's Microfluidics Chip Shows Promise in Cancer Immune Profiling

The first clinical validation of Imec's cell sort chip technology has been reported in Cells through a new collaboration between Imec and the KU Leuven Laboratory of Tumor Immunology and Immunotherapy.

6 Feb 2024

Trapped Inside Tumors: How Dendritic Cells Lose Their Anti-Tumor Abilities

According to new research, certain immune cells in human bodies experience a reduction in their "killer instinct" after entering solid tumors.

5 Feb 2024

NLRC5 Gene Reactivation Boosts Tumor-Killing Immunity

Every human cell has class I major histocompatibility complex (MHC) molecules on its surface, which are immune complexes. The immune system needs MHC class I molecules to identify and eradicate cancer.

30 Jan 2024

mEnrich-seq: A High-Specificity Bacterial Enrichment Technique for Microbiome Research

In a landmark study recently published in the journal Nature Methods, researchers at the Icahn School of Medicine at Mount Sinai have unveiled mEnrich-seq-;an innovative method designed to substantially enhance the specificity and efficiency of research into microbiomes, the complex communities of microorganisms that inhabit the human body.

5 Jan 2024

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

3 Jan 2024

AI-Powered Drug Breakthrough: Insilico Unveils Potent FGFR2/3 Inhibitor for Solid Tumors

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

29 Dec 2023

NUS Scientists Develop Novel Method to Identify and Sort Killer Immune Cells

Our body's immune system is a complex network of organs, cells, and proteins that work in synchrony to protect our bodies against infections caused by pathogens and fight against disease-causing changes in our body, such as the emergence of cancer cells.

20 Dec 2023

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023