Multiple Sclerosis News and Research

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Multiple sclerosis (MS) is a severe autoimmune disease of the central nervous system that affects the brain and spinal cord, causing problems with muscle movement, balance and vision.

Simple inexpensive test determines the genetic susceptibility to PML

Four genetic mutations have been linked to progressive multifocal leukoencephalopathy (PML), a rare but sometimes fatal brain infection that can be provoked by dozens of FDA-approved drugs.

16 Dec 2022

Regeneration of the immune system in MS patients

Transplanting blood stem cells is a new but incredibly successful treatment for multiple sclerosis. Now, a study directed by the University of Zurich has looked closely at how the autoimmune disease is controlled by the treatment and how the immune system recovers afterward.

14 Nov 2022

Revitalized immune cells improve waste removal from the brain

Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.

11 Nov 2022

Resistance against Epstein-Barr virus from experimental monoclonal antibodies

When tested in a lab setting using human cells, a panel of experimental monoclonal antibodies (mAbs) that target various Epstein-Barr virus (EBV) sites prevented infection.

1 Nov 2022

Brain-resident and recruited macrophages exhibit diverging responses

Prof. Kiavash Movahedi (VUB, VIB) headed a group that outlined how the immune system responds to infections entering the brain. The results offer new information on host-pathogen interactions as well as the long-term effects of brain infections.

14 Oct 2022

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022

Simple blood test helps identify patients developing neurotoxic side effects

The treatment of various tumors has been transformed by cell-based immunotherapy, often known as CAR-T cell therapy. To target and combat specific forms of leukemia and lymphoma, the treatment employs genetically engineered T cells.

8 Sep 2022

Improving your Canna-business

In this interview, PerkinElmer, talks to AZoLifeSciences about how you can go about improving your canna-business.

From PerkinElmer 7 Sep 2022

Research findings likely to help identify key differences between effective and flawed immune systems

T cells, a special class of white blood cells, defend the body and kill infected or foreign tissue. In an organ called the thymus, they learn to distinguish between proteins that are helpful and those that are harmful.

8 Aug 2022

Researchers understand how Tenascin proteins slowed down the regeneration process

Tenascin C and Tenascin R, are two proteins that have been the topic of investigation at Ruhr-Universität Bochum. Myelin sheaths, or the sheaths of the nerve cells, are destroyed by immune system cells in this condition.

20 Jun 2022

Researchers shed light on development and treatment of brain diseases

It is highly regulated what goes into the brain and what does not. The phagocytes that encapsulate the blood arteries in the brain and maintain the blood-brain barrier have been examined by researchers at the University of Freiburg’s Faculty of Medicine.

25 Apr 2022

Researchers identify a way to accelerate "handbrake" immune cells to remove disease faster

Researchers at WEHI have discovered a mechanism to boost immune cells, allowing them to remove disease and infections more quickly.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 15 Apr 2022

Study reveals why infected individuals cannot get rid of HIV altogether

Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system.

28 Mar 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

HDO technology found to be effective at silencing problematic genes

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

1 Mar 2022

Central signaling pathway likely to help reduce the progression of autoimmune disorders

When the immune system fails and assaults the body’s own components, autoimmune disorders develop.

25 Feb 2022

In vivo tracking of unlabeled stem cells using sugars

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers -; made out of sugars -; that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Oligodendrocyte plays major role in the development of multiple sclerosis, says study

A team of international researchers revealed that oligodendrocytes, a kind of central nervous system cell, may play a different function in the progression of MS.

2 Feb 2022