Neurons News and Research

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New Synthesis Method Makes Ibogaine More Accessible for Research

Ibogaine, a psychoactive compound derived from plants, has garnered attention for its anti-addictive and anti-depressant properties.

7 Feb 2025

New Brain Cells Could Hold the Key to Regulating Satiation

Columbia scientists have found specialized neurons in the brains of mice that order the animals to stop eating.

6 Feb 2025

Understanding How α2δ Protein Mutations Influence Brain Development in Autism

A recent study has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These mutations significantly reduce the proteins’ membrane expression and synaptic targeting but do not impair calcium channel activity or trans-synaptic signalling.

3 Feb 2025

First Cell Atlas of Focal Cortical Dysplasia Offers New Insights for Treatment

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy.

31 Jan 2025

Researchers Uncover How Fruit Flies Taste Food Texture

A study led by Nikita Komarov and Simon Sprecher at the University of Fribourg, Switzerland, has discovered neurons in the fly larva mouth that allow the taste of food texture.

31 Jan 2025

Fast and Precise Protein Labeling in Intact Tissues with MIT Technology

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility.

27 Jan 2025

Unveiling the Genetic Basis of Mating Behavior in Fruit Flies

The way fruit flies mate could be crucial to preventing mosquitoes from spreading disease.

27 Jan 2025

New Insights into the Biological Basis of Bipolar Disorder

According to research published in Nature on January 22nd, 2025, an international team of psychiatric genetics researchers has discovered 298 regions of the genome with DNA variations that increase the risk for bipolar disorder, more than four times the number previously found.

24 Jan 2025

Segmented Nerve Cords Enable Precision and Flexibility in Cephalopod Arms

Findings on cephalopod nerve cords highlight segmentation's role in sucker movement control, advancing knowledge of neural architectures in soft-bodied species.

24 Jan 2025

Microglia Response Varies Between Male and Female Mice

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and repairing injured tissue.

22 Jan 2025

Mapping of Neuronal IL-1R1 Expression in the Mouse Brain Sheds Light on Mood and Memory

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states.

20 Jan 2025

Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

17 Jan 2025

Is Calcium Signaling the Bridge Between Unicellular and Multicellular Life?

Calcium-dependent signaling in S. rosetta uncovers mechanisms of cellular coordination, shedding light on the evolution of multicellularity and sensory systems.

16 Jan 2025

Scientists Uncover Circuit Controlling Neuron Migration in Brain Development

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

10 Jan 2025

Neuropilin2 Gene Disruption Impacts Brain Circuitry in Autism and Epilepsy

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

10 Jan 2025

Illuminating RNA Function with Innovative Bioluminescent Probes

The molecule that reads the genetic data contained in DNA is called RNA. Researchers at the University of California, Irvine have found a method to tag RNA with a glowing bioluminescent molecule, which enables them to track RNA in real time as it travels throughout the body.

10 Jan 2025

New Discovery Sheds Light on How Monoamines Regulate Brain Rhythms

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

9 Jan 2025

Coordinated Behavior in Choanoflagellates Provides Evolutionary Clues

A new study published in Science Advances reveals evidence of electrical signaling and coordinated behavior in choanoflagellates, the closest living relatives of animals.

9 Jan 2025

Mapping the Aging Brain: A Single-Cell View of Transcriptomic Changes

Research reveals how aging impacts gene expression across brain cell types, identifying critical changes in the hypothalamus linked to health and function.

9 Jan 2025

Epigenetic Clocks Offer Insight into Biological Age at Cell-Type Resolution

A new priority research paper, featured as the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22, was published on December 29, 2024. The paper is titled "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution."

3 Jan 2025