Organoids News and Research

RSS

Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

20 Dec 2023

Exploring the Effects of Vascularization Strategies on Brain Organoids

Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids' development.

18 Dec 2023

Unraveling Stem Cell Destiny in Intestinal Organoids

Stem cells possess the remarkable ability to differentiate and replace deceased or impaired cells within the body.

27 Nov 2023

How 3D-Printed Organs Could Reduce Use of Animal Testing in Medical Research

In the realm of scientific research, particularly in the medical and pharmaceutical sectors, animal testing has been a prevalent method.

22 Nov 2023

Research Reveals How Gut Bacteria Influence Distant Organs Through Oxytocin Signaling

The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the gut.

3 Nov 2023

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023

Regulator Gene for Intestinal Stem Cells Discovered

When a cell dies, a new one has to be formed in its place. This is a regular occurrence in the intestines, where cells are especially exposed to harmful effects.

9 Oct 2023

New Method That Genetically Modifies Individual Cells in Animals

Researchers at ETH Zurich have created a technique that enables them to genetically alter every animal cell in a unique way.

22 Sep 2023

Solving the Dog Epigenome with INTEGRA Biosciences’ Vacuum Aspirations Systems

Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative.

30 Aug 2023

Schizophrenia-Linked Chromosome Deletion Affects Mitochondria

Investigators are learning more about how schizophrenia develops by investigating the most powerful known genetic risk factor.

22 Aug 2023

Stem Cells Used to Create Tooth Enamel in the Lab

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

16 Aug 2023

Novel Matrix Supports Co-Culture of Endometrial Cells

Researchers have developed a synthetic extracellular matrix (ECM) that can facilitate the development of a miniature endometrium in a dish for at least two weeks.

14 Aug 2023

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Oxidative stress, caused by an imbalance of free radicals and antioxidants, regularly reduces the yield of pharmaceuticals and therapeutics produced via bioprocessing by about 10-15%. Now, Xheme, Inc.'s Xheme Multifunctional Additive (XMA), a programmable non-toxic nanoporous microparticle, has demonstrated the ability to significantly reduce or eliminate the damage of oxidative stress in bioprocessing conditions.

25 Jul 2023

New Study Identifies Aerobic Glycolysis Vital for Eye Development

According to a recent Northwestern Medicine study published in Nature Communications, aerobic glycolysis, the process by which cells convert glucose into lactate, is essential for eye development in mammals.

17 Jul 2023

Xenogeneic-Free Brain Organoids Offer New Hope for Studying Neurodegenerative Diseases

Researchers at University of Michigan developed a method to produce artificially grown miniature brains -; called human brain organoids -; free of animal cells that could greatly improve the way neurodegenerative conditions are studied and, eventually, treated.

14 Jul 2023

Location-Dependent Gene Expression in Ovarian Cancer: Insights from 3-D Models

Variations in gene activity based on where a cell is in a tumor have been discovered by researchers with the help of 3-D models of ovarian cancer tumors.

26 Jun 2023

Stem Cell Zoo Uncovers Scaling Laws Governing Species-Specific Development

Pregnancy last around nine months in humans, only 20 days in mice, and up to 17 months in rhinoceroses. Even though many mammalian species go through the same phases of embryo development, the rate of development varies greatly between animals.

21 Jun 2023

iPSC-Based Model System Helps Study Lung-Specific Mesenchyme

Lung mesenchymal cells, which are crucial components of the lung’s distinctive structure, also play a significant role in disease and injury recovery, but research into their biology and how they start disorders like pulmonary fibrosis is limited.

14 Jun 2023

Achieving 3D Printing Inside 'Mini-Organs' Growing in Hydrogels

Scientists from the NIHR Great Ormond Street Hospital Biomedical Research Centre (a collaboration between GOSH and UCL), London, and University of Padova, Italy, have shown for the first time how 3D printing can be achieved inside 'mini-organs' growing in hydrogels -- controlling their shape, activity, and even forcing tissue to grow into 'molds.'

12 Jun 2023