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Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Scientists from the University of Notre Dame have found a new way for tumor cells to transmit genetic material to other cells in their microenvironment, allowing cancer to spread.

1 Apr 2022

Study reveals novel mechanism used by infectious bacteria to survive stressful situations

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections-;such as urinary tract and bloodstream infections like sepsis- are hard to get rid of.

From The University of Utah 24 Mar 2022

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

Biognosys Launches Next-Generation Blood Biomarker Discovery Solution

Biognosys today announces the launch of its next-generation blood biomarker discovery solution, which will be offered as a contract research service.

From Biognosys 10 Nov 2021

New eToeholds could make RNA therapeutics more safer and effective

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

Scientists develop new tool to identify neuronal proteins in animal models

Scientists, for the first time, developed a successful method for pinpointing proteins within different kinds of neurons in the brain of a living animal.

16 Aug 2021

Research provides a detailed 'proteogenomic' view of lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.

6 Aug 2021

Scientists describe pathway that leads to accelerated flowering of plants in low-nitrogen soils

Scientists from Japan, Europe and the USA have described a pathway leading to the accelerated flowering of plants in low-nitrogen soils. These findings could eventually lead to increases in agricultural production.

31 May 2021

Successful class of therapeutics attack and shut down unique and harmful genes

A potential class of therapeutics that uses synthetic nucleic acids to attack and shut down harmful genes while preventing viral spread is gathering momentum.

18 May 2021

Study offers fresh insights into infection process during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

10 Mar 2021

New algorithm identifies 'escaping' cells in single-cell CRISPR screens

A team of researchers from New York has developed a new computational tool to help understand the function and regulation of human genes.

3 Mar 2021

New computational tool reveals the function and regulation of human genes

A new computational tool has been developed by a research team from New York to figure out the regulation and function of human genes.

2 Mar 2021

Study reveals efficient expression system for production of coagulation factor XIIIa

Many reports illustrate that Coagulation factor XIIIa (FXIIIa) has diverse and crucial functions in thrombus for¬mation and stability.

29 Jul 2020

Study explores the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020

Study shows how epigenetics contribute to the development of autoimmune diseases

The human immune system is expected to guard people against the invasion of external microbes, but at times, it possibly leads to autoimmune disorders.

From Osaka University 6 Jul 2020

Foodborne titanium dioxide nanoparticles impact gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

26 Jun 2020

Study reveals mechanism by which propionic acid induces brain disorders

Korea Brain Research Institute (KBRI, headed by Suh Pann-ghill) announced on the 11th that the research team led by Dr. Mun Ji-young revealed the mechanism of autism induced by an imbalance of human gut microorganisms.

19 Jun 2020

Review reveals exceptions to the purported rules of sex chromosome evolution theory

For nearly a century, biologists have modeled the evolution of sex chromosomes--the genetic instructions that primarily determine whether an individual will develop into a male or female (or a certain mating type)--resulting in an impressive theoretical framework.

4 Jun 2020

Research on rare molecule aims to improve treatments for cancer, HIV

Stanford University chemist Paul Wender and his colleagues are working to improve treatments for cancer, HIV and Alzheimer's - and they are betting that a drab, weedy marine invertebrate is the means to achieving that end.

28 Apr 2020