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Study Reveals How the Formation of Microtubules Drives Cell Division

Cellular life hinges on a network of hollow cables called microtubules dynamically lengthening and shortening according to the needs of the moment.

2 May 2023

Argonne's Advanced Photon Source Helps Identify New Antibodies Against Coronaviruses

Results could speed development of new antivirals or vaccines that could counter many different coronavirus variants.

2 May 2023

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

2 May 2023

New Approach Could Power the Development of Advanced Cell Therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

2 May 2023

Biological Condensates Harbor Electrical Imbalances That Spark "Redox" Reactions

The human body relies heavily on electrical charges. Lightning-like pulses of energy fly through the brain and nerves and most biological processes depend on electrical ions traveling across the membranes of each cell in our body.

2 May 2023

Occludin Protein Plays a Critical Role in Cell-to-Cell Transmission of SARS-CoV-2 Virus

While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection -; a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future.

2 May 2023

The Origins of Human Accelerated Regions

Large parts of the human genome were changed over a million years ago due to a random event during egg or sperm formation that resulted in the deletion, duplication, or reversal of sections of DNA. Investigators have demonstrated that those structural variants likely set off a cascade of other fast alterations in human DNA that may underpin unique human traits, particularly the brain.

28 Apr 2023

Study Shows Profound Fluctuations in Gut Microbiome Throughout the Day and Across Seasons

The balance of microbes in the human gut varies substantially from morning to night and even more by season -; with profound fluctuations completely transforming the microbiome from summer to winter, according to a study to be presented at Digestive Disease Week 2023.

28 Apr 2023

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

The April 2023 issue of SLAS Discovery contains six full-length articles and one mini-review covering high-throughput screening (HTS) for protease-inhibiting drugs, high-content phenotypic screening and other life sciences research.

28 Apr 2023

Researchers Identify Genes Responsible for Craniofacial Dysmorphology in Down Syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

27 Apr 2023

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

Computational Models can Help Determine the Identities and Roles of Individual Neurons

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

26 Apr 2023

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks.

26 Apr 2023

New Genetic Mutations Linked to Canine Bladder Cancers Identified

Researchers have identified new genetic mutations linked to a subset of canine bladder cancers. Their findings have implications both for early cancer detection and for targeted treatments in dogs and humans.

26 Apr 2023

New Powerful Resource to Understand the Biology of Extracellular RNA

An international team led by researchers at Baylor College of Medicine with the National Institutes of Health Extracellular RNA Communication Consortium and the Bogdan Mateescu laboratory at the ETH Zürich and University of Zürich has developed a new powerful resource to study extracellular RNA (exRNA), a novel form of cell-to-cell communication.

24 Apr 2023

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

24 Apr 2023

Study Uncovers a Protein-Protein Interaction Related to Parkinson's Disease

In a study published in Nature Communications, a team led by Krembil Brain Institute Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson's disease.

24 Apr 2023

Laboratory News and Research

Study Reveals How the Formation of Microtubules Drives Cell Division

Argonne's Advanced Photon Source Helps Identify New Antibodies Against Coronaviruses

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

New Approach Could Power the Development of Advanced Cell Therapies

Biological Condensates Harbor Electrical Imbalances That Spark "Redox" Reactions

Occludin Protein Plays a Critical Role in Cell-to-Cell Transmission of SARS-CoV-2 Virus

The Origins of Human Accelerated Regions

Study Shows Profound Fluctuations in Gut Microbiome Throughout the Day and Across Seasons

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

Researchers Identify Genes Responsible for Craniofacial Dysmorphology in Down Syndrome

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Computational Models can Help Determine the Identities and Roles of Individual Neurons

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

New Genetic Mutations Linked to Canine Bladder Cancers Identified

New Powerful Resource to Understand the Biology of Extracellular RNA

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Study Uncovers a Protein-Protein Interaction Related to Parkinson's Disease

Abnormal Immune Activity in Astrocytes Causes Dementia-Related Cognitive Deficits

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

Ingenious Approach to Identify AIEgens From Natural Fluorescent Species

Lab Automation - Third Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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