Immune Response News and Research

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Human evolution shaped by pathogens and cell-autonomous immunity

Every human cell harbors its own defenses against microbial invaders, relying on strategies that date back to some of the earliest events in the history of life, researchers report.

10 Sep 2020

Study shows cell surface proteins in placental tissue prevent COVID-19 transmission

Scientists from the Maxwell Finland Laboratory for Infectious Diseases at Boston Medical Center have discovered properties in the placental tissue that may play a significant role in inhibiting the transmission of COVID-19 infection from a mother, who has the novel coronavirus, to her fetus.

3 Sep 2020

Researchers discover link between defensive responses in plants and crop parasite

Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have discovered a link between defensive responses in plants and the beautiful but devastating crop parasite witchweed.

3 Sep 2020

Study reveals a successful strategy to fight influenza

For a long time, influenza scientists have largely focused their studies on the epithelial cells that line the lungs.

2 Sep 2020

New cell atlas can help control mosquito-borne diseases

The first cell atlas of mosquito immune cells recently created by researchers can help interpret how mosquitoes combat various infections, including malaria.

28 Aug 2020

Study sheds light on new element of plant immune defense response to biotic stress

Plants are at the mercy of many stresses, both abiotic, such as drought and heat, and biotic, such as pathogens.

28 Aug 2020

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

Protein structural study may lead to more improved research on disease development

Researchers had identified an actin cytoskeketal nucleator, called Arp2/3 complex, more than 20 years ago.

26 Aug 2020

Macrophage programming allows the body to fight infections and promotes tissue repair

Macrophages are white blood cells that, depending on the signals they get from the immune system, become specialized in either increasing or decreasing inflammation.

26 Aug 2020

New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

Study uncovers how the immune system generates effective antibodies

An in-depth Garvan study of how the immune system generates effective antibodies provides new insights for vaccine design.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

New study shows promise for developing COVID-19 vaccine

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

24 Aug 2020

Study provides detailed map of natural killer cell responses to SARS-CoV-2 infection

A new study of 27 patients hospitalized with COVID-19 has provided a detailed map of natural killer (NK) cell responses to SARS-CoV-2 infection, revealing that specific characteristics of NK cell activation associate with different levels of disease severity.

24 Aug 2020

A metabolic enzyme could be potential target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

21 Aug 2020

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

20 Aug 2020

Immune Response News and Research

Human evolution shaped by pathogens and cell-autonomous immunity

Study shows cell surface proteins in placental tissue prevent COVID-19 transmission

Researchers discover link between defensive responses in plants and crop parasite

Study reveals a successful strategy to fight influenza

New cell atlas can help control mosquito-borne diseases

Study sheds light on new element of plant immune defense response to biotic stress

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Protein structural study may lead to more improved research on disease development

Macrophage programming allows the body to fight infections and promotes tissue repair

New syringe technology for subcutaneous injection of viscous formulations

Study uncovers how the immune system generates effective antibodies

Researchers add a component to make cancer vaccine more effective

New study shows promise for developing COVID-19 vaccine

Study provides detailed map of natural killer cell responses to SARS-CoV-2 infection

A metabolic enzyme could be potential target for immunotherapies

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

Cashew shell compound shows therapeutic potential for demyelinating diseases

Surface structure of SARS-CoV-2 virus offers insights for development of therapeutics

Long-term opioid use in back-pain patients leads to production of anti-opioid antibodies

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