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Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

13 Oct 2020

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

13 Oct 2020

Dopamine and serotonin found to be involved in perception, cognitive capacities

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals -- dopamine and serotonin -- are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

13 Oct 2020

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

It's one of the world's deadliest animals, and it has a taste for human blood: the mosquito. Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Serum antibodies from recovered SARS patients neutralized SARS-CoV-2 in vitro

Antibodies in serum samples collected from patients infected with SARS-CoV during the 2003 outbreak effectively neutralized SARS-CoV-2 infection in cultured cells, according to a new study.

12 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Researchers demonstrate mysterious molecular concept for targeted drug delivery

Researchers have demonstrated a type of cellular binding that could lead to highly targeted treatments against diseases like cancer.

8 Oct 2020

New method reveals structural data of membrane proteins in explicit detail

The human body contains a vast number of proteins that are collectively called the proteome.

8 Oct 2020

Imaging technique could replace invasive tissue biopsies to determine cancer drug resistance

Imaging techniques could replace the need for invasive tissue biopsies in helping rapidly determine whether cancer treatments are working effectively, according to researchers at the University of Cambridge.

7 Oct 2020

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib.

7 Oct 2020

Scientists identify new ingredient that makes vaccine more effective

A number of vaccines contain ingredients known as adjuvants that make them more effective by triggering a more powerful immune response.

5 Oct 2020

Study offers explanation to why people respond differently to the same drug

Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.

5 Oct 2020

Researchers gain insight into potentiating effect of selective drugs

Some highly selective drugs cause unexpected effects in nerve cells: they not only reduce the activation of certain receptors, but also their inactivation.

5 Oct 2020

Scientists discover new genes and brain circuits crucial for short-term memory

A mice study has revealed a novel gene that is crucial for short-term memory but works in a part of the brain that is not usually linked to memory.

5 Oct 2020

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Scientists have discovered a new cellular pathway that can be targeted with a naturally occurring medication to activate the regeneration of lung tissue.

30 Sep 2020

Memory training for the immune system

After an infection of the human body with a pathogen, a cascade of reactions will usually be set into motion.

29 Sep 2020

Genetic variations may not contribute to mortality and morbidity of COVID-19

Researchers did not find any major differences across populations and ethnic groups in seven genes linked to the viral entry of SARS-CoV-2.

25 Sep 2020

Receptor News and Research

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Treatment using immune system T cells preserves vision of mice with retinoblastoma

VAV1 gene mutations may promote growth of T-cell tumors in laboratory mice

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Dopamine and serotonin found to be involved in perception, cognitive capacities

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Serum antibodies from recovered SARS patients neutralized SARS-CoV-2 in vitro

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

Researchers demonstrate mysterious molecular concept for targeted drug delivery

New method reveals structural data of membrane proteins in explicit detail

Imaging technique could replace invasive tissue biopsies to determine cancer drug resistance

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Scientists identify new ingredient that makes vaccine more effective

Study offers explanation to why people respond differently to the same drug

Researchers gain insight into potentiating effect of selective drugs

Scientists discover new genes and brain circuits crucial for short-term memory

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Memory training for the immune system

Genetic variations may not contribute to mortality and morbidity of COVID-19

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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