RNA News and Research

RSS

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

A Study on Gene Silencing Through a Recent Trial

Dr Catherine Mummery, a consultant neurologist at UCL Queen Square Institute of Neurology & the National Hospital for Neurology and Neurosurgery, has led a trial. The trial signifies for the first time that a “gene silencing” method has been taken in Alzheimer’s and dementia disease.

From University College London 27 Apr 2023

A Rapid Method for the Quantitative Detection of miRNA

Researchers investigating the growth of a roundworm discovered a tiny RNA molecule that controlled the expression of specific genes in the early 1990s. This resulted in the discovery of microRNAs (miRNAs), which are now known to exist in all forms of life. These molecules, it turns out, play vital functions in a variety of biological processes.

26 Apr 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Generating the Landscape of m6A in a Mouse Embryo

RNA, particularly mRNA, has recently received some attention as the major component of the COVID-19 vaccines.

26 Apr 2023

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

25 Apr 2023

New Powerful Resource to Understand the Biology of Extracellular RNA

An international team led by researchers at Baylor College of Medicine with the National Institutes of Health Extracellular RNA Communication Consortium and the Bogdan Mateescu laboratory at the ETH Zürich and University of Zürich has developed a new powerful resource to study extracellular RNA (exRNA), a novel form of cell-to-cell communication.

24 Apr 2023

Food-Poisoning Bacteria Create Syringe-Like Structures to Inject Toxins Into Intestinal Cells

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

21 Apr 2023

Using Cellular Reprogramming to Make the Heart Function Like New Again

A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, allowing the heart to function like new again.

20 Apr 2023

MIT Researchers Identify Brain Cells Most Susceptible to Neurodegeneration

Neurodegeneration, or the gradual loss of neuron function, is one of the key features of Alzheimer's disease.

20 Apr 2023

Chemists Propose New Hypothesis for How the First Sugars Arose on the Earth

Two prominent origin-of-life chemists have published a new hypothesis for how the first sugars-;which were necessary for life to evolve-;arose on the early Earth.

17 Apr 2023

New Clinical RNA Sequencing Platform Helps Facilitate Research into Rare Genetic Conditions

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

17 Apr 2023

Researchers Generate Largest Atlas of Post-Zygotic Genome Mutations in Human Tissue Researchers Have ...

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled -; a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

17 Apr 2023

Potential Therapy for Lethal Pediatric Brain Cancer Using ASO Technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

13 Apr 2023

New Method for Improving Gene Therapy With Nanobubbles

Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging-; requiring a new method.

12 Apr 2023

Exceptional Number of Unknown Viruses Found in the Infants' Feces

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

12 Apr 2023

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

According to a study conducted by UCLA, patients with advanced melanoma responded differently to PD-1 checkpoint blockade immunotherapy depending on a variety of variables, including whether or not they had previously received CTLA-4 blockade, another type of immunotherapy.

11 Apr 2023

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 is frequently used to alter the genome by researching and editing disease-related genes. However, this approach is coupled with undesirable side effects including mutations and toxicity.

11 Apr 2023

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Acute myeloid leukemia (AML) is an aggressive blood cancer that causes uncontrolled accumulation of white blood cells. Because of the poor outcomes of this disease, researchers across the globe have been on the hunt for new ways to treat AML, while preserving normal blood development.

10 Apr 2023

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Ribonucleic acid (RNA) molecules are present in all living cells, with different types of RNA having different jobs.

7 Apr 2023

Generation of Monkey Blastoids Using Optimized Protocol

Human embryo development and early organ development remain unclear due to ethical concerns about using embryos for research and a scarcity of materials to investigate.

7 Apr 2023