Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Researchers use new technique to find undetectable ‘hot spots’ inside aggressive breast cancer

Using a new technique, a team of McGill University researchers has found tiny and previously undetectable 'hot spots' of extremely high stiffness inside aggressive and invasive breast cancer tumors.

28 Oct 2020

Scientists develop human airway stem cells to accelerate research on COVID-19, influenza

For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients.

27 Oct 2020

Scientists develop lab-grown lung model to study SARS-CoV-2 infection

A team of Duke University researchers has developed a lab-grown living lung model that mimics the tiny air sacs of the lungs where coronavirus infection and serious lung damage take place. This advance has enabled them to watch the battle between the SARS-CoV-2 coronavirus and lung cells at the finest molecular scale.

23 Oct 2020

New method for producing FTVI enzyme could enhance therapeutic potential of cord blood transplants

A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.

23 Oct 2020

New delivery system may treat male infertility

According to the Mayo Clinic, about 15% of couples are infertile, and male infertility plays a role in over one-third of these cases. Often, problems with sperm development are to blame.

22 Oct 2020

Researchers demonstrate the impact of epithelial cells, mammary microenvironment on breast cancer cells

The cover for issue 30 of Oncotarget features Figure 4, "RNAseq results demonstrating differences between normal, cancer, and redirected cells," by Frank-Kamenetskii, et al. which reported that the influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on breast cancer cells has not.

19 Oct 2020

Synthetic signals could help control tissue regeneration

For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways.

16 Oct 2020

Researchers demonstrate healing power of extracellular vesicles on a heart-on-a-chip

Extracellular vesicles (EVs) -- nanometer sized messengers that travel between cells to deliver cues and cargo -- are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury.

15 Oct 2020

New computational biology algorithm may enable more effective cellular therapies

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders. But a major challenge for cell therapy applications is keeping cells alive and well in the lab.

13 Oct 2020

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

13 Oct 2020

Stem cells that promote bone repair can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

13 Oct 2020

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

13 Oct 2020

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Every eukaryotic organism contains the so-called transposons, which are abundant DNA-elements.

13 Oct 2020

Study offers new insights how the plant tips stay free of virus

Plants are able to keep growing indefinitely because they have tissues made of meristems--plant stem cells--which have the unique ability to transform themselves into the various specialized cells that make up the plant, dividing whenever appropriate and producing new cells of whatever type as needed.

9 Oct 2020

Reducing the harvest period of stem cell sheets to two days

Stem cells are cell factories that constantly divide themselves to create new cells. Implanting stem cells in damaged organs can regenerate new tissues.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Stem Cells News and Research

Further Reading

Researchers use new technique to find undetectable ‘hot spots’ inside aggressive breast cancer

Scientists develop human airway stem cells to accelerate research on COVID-19, influenza

Scientists develop lab-grown lung model to study SARS-CoV-2 infection

New method for producing FTVI enzyme could enhance therapeutic potential of cord blood transplants

New delivery system may treat male infertility

Researchers demonstrate the impact of epithelial cells, mammary microenvironment on breast cancer cells

Synthetic signals could help control tissue regeneration

Researchers demonstrate healing power of extracellular vesicles on a heart-on-a-chip

New computational biology algorithm may enable more effective cellular therapies

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Stem cells that promote bone repair can also generate arthritic bone spurs

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Study offers new insights how the plant tips stay free of virus

Reducing the harvest period of stem cell sheets to two days

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

MIT engineers develop a method to turn off specific genes in bone marrow cells

Researchers develop microelectrode-array chips to measure electrical cell activity

Scientists identify a novel approach to regulate cell plasticity

Cell therapy designed to treat inflammatory bowel disease

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