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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Differentiation protocol can develop safe and efficient pluripotent stem cell-based therapies for AMD

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems.

16 Jun 2022

Integrating Science, Software, and Data to Accelerate Antibody Discovery

As part of our SLAS Europe 2022 coverage, we speak to Andrew LeBeau, Associate Vice President for Product Integrations at Dotmatics, about the importance of managing data within the life sciences and Dotmatic's Biology Solution for Antibody Discovery.

From Society for Laboratory Automation and Screening (SLAS) 16 Jun 2022

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

The identification of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) is the first step in initiating an immune response to viral infection.

13 Jun 2022

New chemical-only process may represent an important breakthrough in creating customized mRNA vaccines

At the Nagoya University in Japan, scientists have come up with a new chemical-only process that might signify an essential discovery in making tailored mRNA vaccines for a range of diseases and enable the low-cost making of mRNA in large quantities.

9 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Cas7-11, the first CRISPR enzyme that can make precise, directed cuts to strands of RNA without hurting cells, was identified and described last year by researchers at MIT’s McGovern Institute for Brain Research.

From Massachusetts Institute of Technology (MIT) 2 Jun 2022

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Proteins are made in cells in the same way as they are made in factories. However, making too much at the wrong moment may lead to illnesses like cancer, so they use RNA interference (RNAi) to regulate production.

1 Jun 2022

Researchers determine intracellular antibodies to cure diseases

Mermaid Bio GmbH of Munich, Germany, and WEHI of Melbourne, Australia, recently announced cooperation to identify and develop a unique class of therapeutic candidates that modify misbehaving proteins inside cells that can cause a variety of diseases.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 1 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists from Kumamoto University used next-generation sequencing to analyze human endogenous retrovirus (HERV) integration sites and found that these primitive retroviruses can retrotranspose (DNA sequence insertion with RNA mediation) into iPS cells.

31 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

From The Max Planck Institute 27 May 2022

RNA News and Research

Differentiation protocol can develop safe and efficient pluripotent stem cell-based therapies for AMD

Integrating Science, Software, and Data to Accelerate Antibody Discovery

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

New chemical-only process may represent an important breakthrough in creating customized mRNA vaccines

Study identifies the regulatory function of non-coding 7S RNA

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Researchers determine intracellular antibodies to cure diseases

Research shows how current drugs impact bacterial physiology

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Researchers develop a new biochemical process to analyze plant immunity

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

New chemical technique with CRISPR gene-editing tool helps to cure genetic diseases

Researchers introduce CRISPR to enable gene editing in cockroaches

Research highlights how microbe-free mice absorb fat using different sets of genes

Researchers create open-access atlases of human immune cells in adults

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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